205756-23-6

Basic information

• Product Name: 2'-amino-5'-chloro-3'-hydroxy-2,2,2-trifluoroacetophenone
• Synonyms: 2'-amino-5'-chloro-3'-hydroxy-2,2,2-trifluoroacetophenone
• CAS NO: 205756-23-6
• Molecular Weight: 239.581
• Mol File: 205756-23-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2'-amino-5'-chloro-3'-hydroxy-2,2,2-trifluoroacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-amino-5'-chloro-3'-hydroxy-2,2,2-trifluoroacetophenone(205756-23-6)
• EPA Substance Registry System: 2'-amino-5'-chloro-3'-hydroxy-2,2,2-trifluoroacetophenone(205756-23-6)

Safety Data

• Hazardous Substances Data: 205756-23-6(Hazardous Substances Data)

Upstream product

• 205756-22-5 2'-amino-5'-chloro-3'-methoxy-2,2,2-trifluoroacetophenone 
• 113137-29-4 N-(4-chloro-2-methoxyphenyl)-2,2-dimethylpropanamide 
• 93-50-5 4-chloro-o-anisidine 
• 6627-53-8 1-chloro-3-methoxy-4-nitrobenzene 

Downstream Products

• 205756-24-7 2'-amino-5'-chloro-3'-(t-butyldimethylsilyloxy)-2,2,2-trifluoroacetophenone 
• 1027042-31-4 8-(tert-butyl-dimethyl-silanyloxy)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 205756-25-8 2-(2-Amino-5-chloro-3-(t-butyldimethylsilyloxy)-phenyl)-4-cyclopropyl-1,1,1-trifluoro-3-butyn-2-ol 
• 205754-32-1 6-chloro-4-cyclopropylethynyl-8-hydroxy-4-trifluoromethyl-1,4-dihydro-benzo[d][1,3]oxazin-2-one 
• 205754-33-2 8-Hydroxyefavirenz 

Relevant articles and documents

Synthesis and biological activities of potential metabolites of the non-nucleoside reverse transcriptase inhibitor efavirenz

Studies on the biotransformation of the clinically important non-nucleoside reverse transcriptase inhibitor efavirenz have shown that oxidation and secondary conjugation are important components of the processing of this molecule in vivo. We have synthesized metabolites of efavirenz to confirm their structure and to evaluate their activity as antivirals.