205756-30-5

Basic information

• Product Name: 2-amino-N-methoxy-N,5-dimethylBenzamide
• Synonyms: 2-amino-N-methoxy-N,5-dimethylBenzamide
• CAS NO: 205756-30-5
• Molecular Weight: 194.233
• Mol File: 205756-30-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-amino-N-methoxy-N,5-dimethylBenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-N-methoxy-N,5-dimethylBenzamide(205756-30-5)
• EPA Substance Registry System: 2-amino-N-methoxy-N,5-dimethylBenzamide(205756-30-5)

Safety Data

• Hazardous Substances Data: 205756-30-5(Hazardous Substances Data)

Usage

General Description

2-amino-N-methoxy-N,5-dimethylBenzamide is a chemical compound with the molecular formula C11H16N2O2. It is a benzamide derivative with a methyl group attached to the 5th position of the benzene ring, as well as an amino and methoxy group attached to the nitrogen atom. 2-amino-N-methoxy-N,5-dimethylBenzamide has potential applications in pharmaceutical research and drug development due to its structural features and potential pharmacological properties. It may be of interest for its potential as a drug candidate or as a chemical building block for the synthesis of other compounds. Further studies and research are needed to fully understand the properties and potential uses of this chemical.

Upstream product

• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 4692-99-3 6-methyl-1H-benzo[d][1,3]oxazine-2,4-dione 

Downstream Products

• 133436-18-7 (2-amino-5-methylphenyl)(4-chlorophenyl)methanone 
• 1449372-75-1 (2-amino-5-methylphenyl)(3-fluorophenyl)methanone 
• 1449373-73-2 4-(4-chlorophenyl)-3-[5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl]-6-methylquinolin-2(1H)-one 
• 1449373-74-3 3[(5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-3-yl)]-4-(3-fluorophenyl)-6-methylquinolin-2(1H)-one 
• 1449374-18-8 4-{5-(4-chlorophenyl)-3-[4-(4-chlorophenyl)-6-methyl-2-oxo-1,2-dihydroquinolin-3-yl]-4,5-dihydro-1H-pyrazol-1-yl}-4-oxobutanoic acid 
• 1449374-19-9 4-{5-(4-chlorophenyl)-3-[4-(3-fluorophenyl)-6-methyl-2-oxo-1,2-dihydroquinolin-3-yl]-4,5-dihydro-1H-pyrazol-1-yl}-4-oxobutanoic acid 
• 1449372-92-2 3-acetyl-4-(4-chlorophenyl)-6-methylquinolin-2(1H)-one 
• 1449372-93-3 3-acetyl-4-(3-fluorophenyl)-6-methylquinolin-2(1H)-one 
• 1449373-28-7 (E)-4-(4-chlorophenyl)-3-[3-(4-chlorophenyl)acryloyl]-6-methylquinolin-2(1H)-one 
• 1449373-29-8 (E)-3-[3-(4-chlorophenyl)acryloyl]-4-(3-fluorophenyl)-6-methylquinolin-2(1H)-one 
• 17852-28-7 2-amino-5-methylbenzophenone 
• 52107-75-2 6-Iod-3-methylbenzophenon 

Relevant articles and documents

One-Pot Synthesis of Spirocyclopenta[ a]indene Derivatives via a Cascade Ring Expansion and Intramolecular Friedel-Crafts-Type Cyclization

A one-pot efficient synthetic approach for the rapid construction of spirocyclopenta[a]indene derivatives has been developed via an iodine-initiated cascade ring expansion and intramolecular Friedel-Crafts-type cyclization from propargyl alcohol-tethered alkylidenecyclobutanes under mild conditions with broad substrate scope. This cascade process can be elegantly conducted on a gram scale. A plausible reaction mechanism has been proposed on the basis of a series of deuterium labeling and control experiments.

Rapid construction of cyclopenta[: B] naphthalene frameworks from propargylic alcohol tethered methylenecyclopropanes

We have developed a new synthetic methodology for the rapid construction of cyclopenta[b]naphthalene frameworks from the reaction of propargylic alcohol tethered methylenecyclopropanes with mesyl chloride in the presence of triethylamine through cascade cyclization. The reaction can be performed under mild conditions without the use of transition metals, affording the target products in moderate to good yields, and this cyclization reaction process can be scaled up to a gram-scale synthesis.

Synthesis of Diiodinated All-Carbon 3,3′-Diphenyl-1,1′-spirobiindene Derivatives via Cascade Enyne Cyclization and Electrophilic Aromatic Substitution

A synthetic method for the construction of diiodinated all-carbon spirobiindene derivatives has been developed from the reaction of propargyl alcohol-tethered alkylidenecyclopropanes with iodine. The reaction proceeded through an iodination-initiated cascade intramolecular enyne cyclization and electrophilic aromatic substitution reaction process in 1,2-dichloroethane upon heating, giving desired spirocyclic products in moderate to excellent yields. Further transformation of the obtained products has also been presented.