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DIETHYLSULFAMOYL CHLORIDE, also known as DESC, is an organosulfur compound characterized by its chemical formula C4H10ClNO2S. It is a colorless liquid with a pungent odor, known for its high reactivity and corrosive properties. DIETHYLSULFAMOYL CHLORIDE is a significant reagent in various organic synthesis processes, particularly within the pharmaceutical sector.

20588-68-5

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20588-68-5 Usage

Uses

Used in Pharmaceutical Industry:
DIETHYLSULFAMOYL CHLORIDE is used as a reagent for the synthesis of sulphonamides and other related chemicals, which are crucial in the development of various pharmaceutical products.
Used in Agrochemical Production:
In the agrochemical industry, DIETHYLSULFAMOYL CHLORIDE is utilized as a precursor in the manufacturing of insecticides and herbicides, contributing to the development of products that protect crops from pests and weeds.
Due to its corrosive and toxic nature, it is imperative that DIETHYLSULFAMOYL CHLORIDE is handled with strict safety measures and appropriate protective equipment to ensure the safety of individuals and the environment.

Check Digit Verification of cas no

The CAS Registry Mumber 20588-68-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,0,5,8 and 8 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 20588-68:
(7*2)+(6*0)+(5*5)+(4*8)+(3*8)+(2*6)+(1*8)=115
115 % 10 = 5
So 20588-68-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H10ClNO2S/c1-3-6(4-2)9(5,7)8/h3-4H2,1-2H3

20588-68-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name N,N-diethylsulfamoyl chloride

1.2 Other means of identification

Product number -
Other names diethylamidosulfonic acid chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:20588-68-5 SDS

20588-68-5Relevant academic research and scientific papers

Nickel-Catalyzed Hydrodeoxygenation of Aryl Sulfamates with Alcohols as Mild Reducing Agents

Matsuo, Kasumi,Kuriyama, Masami,Yamamoto, Kosuke,Demizu, Yosuke,Nishida, Koyo,Onomura, Osamu

, p. 4449 - 4460 (2021/08/25)

The nickel-catalyzed hydrodeoxygenation of aryl sulfamates has been developed with alcohols as mild reductants. A variety of functional groups and heterocycles were tolerated in this reaction system to give the desired products in high yields. In addition, the gram-scale process and stepwise cine-substitution were also achieved with high efficiency.

Sulfonamide derivatives of cis-imidazolines as potent p53-MDM2/MDMX protein-protein interaction inhibitors

Bazanov, Daniil R.,Kopeina, Gelina S.,Lozinskaya, Natalia A.,Maksutova, Anita I.,Pervushin, Nikolay V.,Savin, Egor V.,Sosonyuk, Sergey E.,Tsymliakov, Michael D.

, p. 2216 - 2227 (2021/10/14)

p53-MDM2/MDMX interaction inhibitors represent the prospective agents for targeted anticancer therapy in tumors expressing wild-type p53 protein. Imidazoline-based MDM2-targeted inhibitors of such type, nutlins, contain halogen-substituted phenyl rings, w

Quinoline-based compound and selective androgen receptor agonist comprising the same

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Paragraph 0505-0507, (2016/10/08)

Provided are a novel quinoline-based compound, a pharmaceutical composition containing the quinoline-based compound, and a method for producing the quinoline-based compound. The quinoline-based compound acts on an androgen receptor to increase activities of the androgen receptor, and thus can be favorably used as an agent for treating and preventing diseases or conditions, in which the increased activities of the androgen can lead to improvement of symptoms or the responsiveness to treatment, for example, various hormone-related diseases of the male or female, muscle-wasting disease, osteoporosis, and the like.COPYRIGHT KIPO 2016

Compositions for Treatment of Cystic Fibrosis and Other Chronic Diseases

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Paragraph 2611, (2015/09/22)

The present invention relates to pharmaceutical compositions comprising an inhibitor of epithelial sodium channel activity in combination with at least one ABC Transporter modulator compound of Formula A, Formula B, Formula C, or Formula D. The invention also relates to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis using the pharmaceutical combination compositions.

Benzimidazole Derivatives, Compositions Containing Them, Preparation Thereof and Uses Thereof

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Page/Page column 11, (2008/12/08)

Compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

COMPOUNDS, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF III

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Page/Page column 18; 19, (2008/06/13)

Compounds of Formula I, or pharmaceutically acceptable salts thereof: I (chemical formula to be inserted here - please see paper copy) wherein R1, R2, R3, R4, R5, R6 and G are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

BENZIMIDAZOLE DERIVATIVES, COMPOSITIONS CONTAINING THEM, PREPARATION THEREOF AND USES THEREOF

-

Page/Page column 26-27, (2008/06/13)

Compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

Process for producing aromatic compound derivative by reaction of aromatic compound substituted with sulfamoyloxy, sulfinamoyloxy, or carbamoyloxy group, with nucleophilic agent

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Page/Page column 25; 26, (2008/06/13)

A process for producing a compound represented by the following formula (I), which includes causing a compound represented by formula (II) to react with a nucleophilic agent: wherein X represents a substituent; R1 represents an electron-withdrawing substituent having a Hammett σp constant of more than 0; m represents an integer of 1 to 5; R2 represents a substituent; n represents an integer of 0 to 4; and m + n is from 1 to 5; wherein R1, m, R2, and n each have the same meanings to those in formula (I); R3 and R4 each independently represent an alkyl, aryl, or heterocyclic group; and Z represents C=O or S(O)p, wherein p is 1 or 2.

Acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and their use as antiproliferative agents

-

, (2008/06/13)

The present invention is directed to acyl and sulfonyl derivatives of 6,9-disubstituted 2-(trans-1,4-diaminocyclohexyl)-purines and methods of using the same as antiproliferative agents or to prevent apoptosis.

Synthesis and structure of 2-N,N-dimethyl- and 2-N,N-diethylsulfamoyl-1-(3-indolyl)-1,2-dihydroisoquinolines

Skrypnik,Vasil'eva,Lyashchuk,Bezrodnyi,Enya

, p. 577 - 580 (2007/10/03)

New sulfamoyl derivatives of (3-indolyl)-1,2-dihydroisoquinoline were prepared by reaction of isoquinoline and indole with sulfamoyl chlorides. The compounds were shown to exist in two isomeric forms by semiempirical quantum-chemical calculation in AMl ap

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