20588-68-5

Basic information

• Product Name: DIETHYLSULFAMOYL CHLORIDE
• Synonyms: sulfamoyl chloride, diethyl-;diethylsulfamoyl chloride(SALTDATA: FREE);N,N-diethylsulfamoyl chloride;N,N-Diethyl sulphamoyl chloride
• CAS NO: 20588-68-5
• Molecular Formula: C₄H₁₀ClNO₂S
• Molecular Weight: 171.65
• Mol File: 20588-68-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 223.6°C at 760 mmHg
• Flash Point: 89.1°C
• Appearance: /
• Density: 1.278g/cm³
• Vapor Pressure: 0.0952mmHg at 25°C
• Refractive Index: 1.479
• PKA: -8.42±0.70(Predicted)
• CAS DataBase Reference: DIETHYLSULFAMOYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: DIETHYLSULFAMOYL CHLORIDE(20588-68-5)
• EPA Substance Registry System: DIETHYLSULFAMOYL CHLORIDE(20588-68-5)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 20588-68-5(Hazardous Substances Data)

Usage

General Description

DIETHYLSULFAMOYL CHLORIDE, also known as DESC, is an organosulfur compound with the chemical formula C4H10ClNO2S. It is a colorless liquid with a pungent odor, and is highly reactive and corrosive. DESC is commonly used as a reagent in organic synthesis, particularly in the pharmaceutical industry, for the production of sulphonamides and other chemicals. It is also used as a precursor in the manufacturing of insecticides and herbicides. Due to its corrosive and toxic nature, handling of DIETHYLSULFAMOYL CHLORIDE requires careful safety precautions and proper protective equipment.

InChI:InChI=1/C4H10ClNO2S/c1-3-6(4-2)9(5,7)8/h3-4H2,1-2H3

Upstream product

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Downstream Products

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• 64795-23-9 CQ 32-084 
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Relevant articles and documents

Nickel-Catalyzed Hydrodeoxygenation of Aryl Sulfamates with Alcohols as Mild Reducing Agents

The nickel-catalyzed hydrodeoxygenation of aryl sulfamates has been developed with alcohols as mild reductants. A variety of functional groups and heterocycles were tolerated in this reaction system to give the desired products in high yields. In addition, the gram-scale process and stepwise cine-substitution were also achieved with high efficiency.

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Provided are a novel quinoline-based compound, a pharmaceutical composition containing the quinoline-based compound, and a method for producing the quinoline-based compound. The quinoline-based compound acts on an androgen receptor to increase activities of the androgen receptor, and thus can be favorably used as an agent for treating and preventing diseases or conditions, in which the increased activities of the androgen can lead to improvement of symptoms or the responsiveness to treatment, for example, various hormone-related diseases of the male or female, muscle-wasting disease, osteoporosis, and the like.COPYRIGHT KIPO 2016

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