206547-69-5Relevant articles and documents
The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P11 groups
Levin,Chen,Du,Hogan,Kincaid,Nelson,Venkatesan,Wehr,Zask,DiJoseph,Killar,Skala,Sung,Sharr,Roth,Jin,Cowling,Mohler,Black,March,Skotnicki
, p. 2189 - 2192 (2007/10/03)
A novel series of anthranilic acid-based inhibitors of MMP-1, MMP-9, MMP-13, and TACE was prepared and evaluated. Selective inhibitors of MMP-9, MMP-13, and TACE were identified, including the potent, orally active MMP-13 inhibitor 4p.