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206551-41-9

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206551-41-9 Usage

Chemical Properties

off-white powder

Check Digit Verification of cas no

The CAS Registry Mumber 206551-41-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,0,6,5,5 and 1 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 206551-41:
(8*2)+(7*0)+(6*6)+(5*5)+(4*5)+(3*1)+(2*4)+(1*1)=109
109 % 10 = 9
So 206551-41-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H6BrFO2/c1-12-8(11)5-3-2-4-6(9)7(5)10/h2-4H,1H3

206551-41-9 Well-known Company Product Price

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  • Alfa Aesar

  • (H36865)  Methyl 3-bromo-2-fluorobenzoate, 98%   

  • 206551-41-9

  • 1g

  • 1078.0CNY

  • Detail
  • Alfa Aesar

  • (H36865)  Methyl 3-bromo-2-fluorobenzoate, 98%   

  • 206551-41-9

  • 5g

  • 3597.0CNY

  • Detail

206551-41-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 3-bromo-2-fluorobenzoate

1.2 Other means of identification

Product number -
Other names CK1098

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:206551-41-9 SDS

206551-41-9Downstream Products

206551-41-9Relevant articles and documents

Enantioselective Total Synthesis of Beraprost Using Organocatalyst

Umemiya, Shigenobu,Sakamoto, Daisuke,Kawauchi, Genki,Hayashi, Yujiro

supporting information, p. 1112 - 1115 (2017/03/14)

A convergent and enantioselective total synthesis of the most active isomer of beraprost was achieved in 17 pots. A unique tricyclic core in beraprost was synthesized efficiently by utilizing the asymmetric organocatalyst-mediated formal [3 + 2] cycloaddi

Discovery of dabrafenib: A selective inhibitor of Raf Kinases with antitumor activity against B-Raf-driven tumors

Rheault, Tara R.,Stellwagen, John C.,Adjabeng, George M.,Hornberger, Keith R.,Petrov, Kimberly G.,Waterson, Alex G.,Dickerson, Scott H.,Mook, Robert A.,Laquerre, Sylvie G.,King, Alastair J.,Rossanese, Olivia W.,Arnone, Marc R.,Smitheman, Kimberly N.,Kane-Carson, Laurie S.,Han, Chao,Moorthy, Ganesh S.,Moss, Katherine G.,Uehling, David E.

supporting information, p. 358 - 362 (2013/05/09)

Hyperactive signaling of the MAP kinase pathway resulting from the constitutively active B-RafV600E mutated enzyme has been observed in a number of human tumors, including melanomas. Herein we report the discovery and biological evaluation of GSK2118436, a selective inhibitor of Raf kinases with potent in vitro activity in oncogenic B-Raf-driven melanoma and colorectal carcinoma cells and robust in vivo antitumor and pharmacodynamic activity in mouse models of B-RafV600E human melanoma. GSK2118436 was identified as a development candidate, and early clinical results have shown significant activity in patients with B-Raf mutant melanoma.

TRICYCLIC INHIBITORS OF KINASES

-

Page/Page column 85, (2012/09/10)

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein X, Y, Z, R3 and R4 are defined in the description. The present invention relates also to compositions containing said compounds which are useful for inhibiting kinases such as wee-1 and methods of treating diseases such as cancer.

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