206983-89-3Relevant academic research and scientific papers
Elucidation of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis: Straightforward syntheses of enantiopure 1-deoxy-D-xylulose from pentose derivatives
Hoeffler, Jean-Fran?ois,Grosdemange-Billiard, Catherine,Rohmer, Michel
, p. 3065 - 3067 (2007/10/03)
Optically pure 1-deoxy-D-xylulose, a key metabolite for feeding experiments in the methylerythritol phosphate pathway for isoprenoid biosynthesis, is conveniently synthesised from 1,2-O-isopropylidene-α-D-xylofuranose or from D-arabinose. This renders lab
New and efficient synthetic routes to 1-deoxy-D-xylulose
Giner, Jose-Luis
, p. 2479 - 2482 (2007/10/03)
The biochemically important deoxysugar 1-deoxy-D-xylulose was synthesized by improved methods. D-Tartaric acid is the starting material for a synthesis which proceeds via the intermediacy of 2,3,4-tribenzyl-D- threitol. Another, highly efficient route use, the Sharpless asymmetric dihydroxylation of 5-benzyloxy-3-penten-2-one as its key step. These syntheses are especially useful-for isotopic labelling.
