20717-86-6Relevant articles and documents
Palladium-catalyzed cross-coupling of benzyltitanium(IV) reagents with aryl fluorides
Li, Yan
, (2022/01/11)
The first palladium-catalyzed cross-coupling between benzyltitanium(IV) reagents with aryl fluorides is reported. A variety of diarylmethanes can be prepared in good to excellent yields by the catalyst system of PdCl2(dppf)2 associated with 1-[2-(di-tert-butylphosphanyl)phenyl]-4-methoxypiperidine. This reaction offered a highly efficient approach to diarylmethanes that are commonly found in life-changing drug molecules. Graphical abstract: [Figure not available: see fulltext.]
Method for Catalytic Enantioselective Alkylation of Aldehydes Using Grignard Reagents as Alkyl Sources
Tanaka, Kento,Tomihama, Munehisa,Yamamoto, Koji,Matsubara, Naoki,Harada, Toshiro
, p. 6127 - 6132 (2018/05/23)
Alkyltitanium reagents, generated in situ from Grignard reagents and ClTi(OiPr)3, can be employed without further manipulation in the enantioselective alkylation of aldehyde by the catalysis of a chiral titanium complex derived from DTBP-H8-BINOL. The reaction is performed with good stoichiometry [1.5 equiv each of Grignard reagents and ClTi(OiPr)3] at a low catalyst loading (2 mol %), affording a variety of chiral secondary alcohols in high enantioselectivity and yields and, hence, realizing an asymmetric version of the Grignard reaction in an indirect manner.
GROUP 4 METAL COMPLEX, PRODUCTION METHOD THEREOF, PREPARATION METHOD OF GROUP 4 METAL-CONTAINING THIN FILM
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Paragraph 0076; 0079, (2018/10/03)
PROBLEM TO BE SOLVED: To provide a group 4 metal complex having excellent thermal stability and proper vapor pressure and suitable as a material for preparing a group 4 metal-containing thin film. SOLUTION: There is provided the group 4 metal complex represented by the general formula (1), where M represents a group 4 metal atom, R1, R2, R3 and R4 each represent independently a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, R5, R6 and R7 each represent independently an alkyl group having 1 to 8 carbon atoms, R8, R9 and R10 each represent independently an alkyl group having 1 to 6 carbon atoms or a di (alkyl having 1 to 3 carbon atoms) amino group. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPO&INPIT