20721-78-2

Basic information

• Product Name: 4-methylmorpholin-3-one
• Synonyms: 3-morpholinone, 4-methyl-; 4-Methylmorpholin-3-one
• CAS NO: 20721-78-2
• Molecular Formula: C₅H₉NO₂
• Molecular Weight: 115.1305
• Mol File: 20721-78-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 240.9°C at 760 mmHg
• Flash Point: 99.5°C
• Density: 1.095g/cm³
• Vapor Pressure: 0.0369mmHg at 25°C
• Refractive Index: 1.454
• CAS DataBase Reference: 4-methylmorpholin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methylmorpholin-3-one(20721-78-2)
• EPA Substance Registry System: 4-methylmorpholin-3-one(20721-78-2)

Safety Data

• Hazardous Substances Data: 20721-78-2(Hazardous Substances Data)

Usage

General Description

4-Methylmorpholin-3-one, also known as N-Methylmorpholin-3-one, is a chemical compound with the molecular formula C5H9NO2. It is a heterocyclic organic compound that contains a morpholine ring with a methyl group attached at the 4-position and a ketone group at the 3-position. It is commonly used as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals due to its versatile reactivity and potential for forming a wide range of chemical bonds. 4-Methylmorpholin-3-one is also used as a solvent and intermediate in organic synthesis. It is a colorless liquid with a slightly amine-like odor and is commercially available from various chemical suppliers.

Upstream product

• 109-11-5 morpholine-3-one 
• 74-88-4 methyl iodide 
• 109-02-4 4-methyl-morpholine 
• 105-39-5 chloroacetic acid ethyl ester 
• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 120829-29-0 2-<1-hydroxy-1,1-diphenylmethyl>-4-methyl-3-morpholinone 
• 128407-14-7 2-<(benzoylamino)(phenyl)methyl>-4-methyl-3-morpholinone 
• 128407-15-8 2-(1-benzoylamino-1,1-diphenylmethyl)-4-methyl-3-morpholinone 
• 225506-78-5 4-methyl-2-<1-(3-chlorophenyl)-1-(phenylamino)-methyl>-3-morpholinone 
• 225506-77-4 4-methyl-2-<1-(2-chlorophenyl)-1-(phenylamino)-methyl>-3-morpholinone 
• 225506-81-0 4-methyl-2-<1-(3-methoxyphenyl)-1-(phenylamino)-methyl>-3-morpholinone 
• 225506-76-3 4-methyl-2-(1-phenylamino-1-phenylmethyl)-3-morpholinone 
• 444792-77-2 2-<1-hydroxy-1-(4-methoxyphenyl)methyl>-4-methyl-3-morpholinone 
• 225506-79-6 4-methyl-2-<1-(4-chlorophenyl)-1-(phenylamino)-methyl>-3-morpholinone 
• 225506-82-1 4-methyl-2-<1-(4-methoxyphenyl)-1-(phenylamino)-methyl>-3-morpholinone 
• 153807-04-6 (+)-(1R,4R,5R,6S)-5,6-dihydroxybicyclo<2.2.1>heptan-2-one 

Relevant articles and documents

SYNTHESIS AND CARBENE DECOMPOSITION OF FUNCTIONALLY-SUBSTITUTED DIAZOACETIC ESTERS. 4. 2-AMINOETHYL DIAZOACETATES AND N-(2-HYDROXYETHYL)-N-ALKYLDIAZOACETAMIDES

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3-(Imidazolyl)-2-alkoxypropanoic acids

Compounds according to formula (I) wherein n is 0-3, R1 is optionally substituted C1-6 alkyl, C2-6 alkenyl, or C2-6 alkynyl, Heterocycle, Aromatic heterocycle, Aryl or hydrogen and R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from hydrogen and optionally substituted C1-6 alkyl, or R5 and R8 are an alkylene chain, are novel. They are useful in the treatment of thrombotic conditions and other pathologies associated with fibrin deposition.

GIF OXIDATION OF SOME ALICYCLIC AMINES

The Gif oxidation of seven alicyclic tertiary amines leads essentially to the formation of lactams.The structure of the products present in trace amounts supports the mechanistic hypothesis previously advanced.The structures of the oxidation products were investigated using high performance GC-MS system.