20765-68-8Relevant academic research and scientific papers
Convenient N-acetylation of amines in N,N-dimethylacetamide with N,N-carbonyldiimidazole
Chikkulapalli, Anil,Aavula, Sanjeev Kumar,Mona Np, Rifahath,Karthikeyan, Karthikeyan,Kumar C.H., Vinodh,Sulur G., Manjunatha,Sumathi, Shanmugam
, p. 3799 - 3803 (2015)
Dimethylacetamide (DMAc) acts as an efficient source of acetyl and dimethylamine gas in the presence of N,N-carbonyldiimidazole (CDI). Addition of amines to the reaction mixture delivers the corresponding amides in good to excellent yields. The acetylation of amines reported herein, which relies on the in situ generation of N-acetylimidazole on warming of DMAc with CDI at 120-125 °C, serves as a convenient alternative to other acetylation methods.
The Direct Synthesis of Secondary Amides from Aldehydes; A Novel General Redox Procedure Mediated by Iodotrichlorosilane (ITCS)
Elmorsy, Saad S.,Badawy, Doria S.,Nour, Mohamed A.,Kandeel, Ezzat M.
, p. 417 - 421 (2007/10/02)
A unique, general redox process for the preparation of secondary amides by the interaction, of aldehydes with nitriles in the presence of two equivalents of iodotrichlorosilane (ITCS) is described and possible pathways are discussed. - Keywords: Iodotrichlorosilane, Aldehydes, Nitriles, sec-Amides
A NOVEL ROUTE FOR THE DIRECT SYNTHESIS OF SECONDARY AMIDES FROM ALDEHYDES
Elmorsy, Saad S.,Nour, Mohamed A.,Kandeel, Ezzat M.,Pelter, Andrew
, p. 1825 - 1826 (2007/10/02)
We describe a unique, general redox process for the preparation of secondary amides by the interaction of aldehydes and nitriles in the presence of two equivalents of iodotrichlorosilane (ITCS).
