20776-60-7

Basic information

• Product Name: 2-AMINO-5,6-DICHLOROBENZOIC ACID
• Synonyms: 6-AMINO-2,3-DICHLORO-BENZOIC ACID;2-AMINO-5,6-DICHLOROBENZOIC ACID;BUTTPARK 49\07-43;RARECHEM AL BO 2014;2-Amino-5,6-dichlorobenzoic acid ,97%
• CAS NO: 20776-60-7
• Molecular Formula: C₇H₅Cl₂NO₂
• Molecular Weight: 206.03
• Mol File: 20776-60-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 176-177 °C (decomp)
• Boiling Point: 369.2°C at 760 mmHg
• Flash Point: 177.1°C
• Appearance: /
• Density: 1.607g/cm³
• Vapor Pressure: 4.21E-06mmHg at 25°C
• Refractive Index: 1.658
• Storage Temp.: 2-8°C
• PKA: 0.53±0.25(Predicted)
• CAS DataBase Reference: 2-AMINO-5,6-DICHLOROBENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-5,6-DICHLOROBENZOIC ACID(20776-60-7)
• EPA Substance Registry System: 2-AMINO-5,6-DICHLOROBENZOIC ACID(20776-60-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 20776-60-7(Hazardous Substances Data)

Usage

General Description

2-Amino-5,6-dichlorobenzoic acid is a chemical compound that belongs to the class of benzoic acids. It is a derivative of benzoic acid, with two chlorine atoms attached to the fifth and sixth carbon atoms, and an amino group attached to the second carbon atom. 2-AMINO-5,6-DICHLOROBENZOIC ACID is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used in research as a reagent in various chemical reactions. 2-Amino-5,6-dichlorobenzoic acid is considered to be a potentially hazardous substance, and proper safety precautions should be taken when handling it.

InChI:InChI=1/C7H5Cl2NO2/c8-3-1-2-4(10)5(6(3)9)7(11)12/h1-2H,10H2,(H,11,12)

Upstream product

• 1677-47-0 4,5-Dichloro-1H-indole-2,3-dione 
• 6334-18-5 2,3-dichlorobenzylaldehyde 
• 6344-05-4 4-chloroisatin 
• 13300-62-4 2,3-dichloro-6-nitrobenzoic acid 
• 6662-53-9 N-(α-Oximino-acetyl)-3.4-dichlor-anilin 

Downstream Products

• 70380-51-7 3,4-dichloro-2-hydroxymethylaniline 
• 58579-51-4 anagrelide hydrochloride 
• 68475-42-3 anagrelide 
• 857601-95-7 6-(carboxymethyl-amino)-2,3-dichloro-benzoic acid 
• 95-76-1 m,p-dichloroaniline 

Relevant articles and documents

FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF

AbstractNovel compounds of the following formula (I) and pharmacologically acceptable salt and esters thereof can modulate LXR function and as a result show excellent anti-arteriosclerotic and anti-inflammatory activity:wherein:A represents aryl or heteroaryl;R1, R2 and R3 are the same or different and each represents hydrogen, hydroxyl, nitro, cyano, amino, halogen, carboxy, carbamoyl, mercapto, alkyl, haloalkyl, alkylcarbonyloxy, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, dialkylamino, alkylcarbonylamino, N-(alkylcarbonyl)-N-(alkyl)amino, alkoxycarbonylamino, N-(alkoxycarbonyl)-N-(alkyl)amino, alkylsulfonylamino, N-(alkylsulfonyl)-N-(alkyl)amino, haloalkylsulfonylamino, N-(haloalkylsulfonyl)-N-(alkyl)amino, alkylcarbonyl, alkoxycarbonyl, alkylaminocarbonyl or dialkylaminocarbonyl group, or R1 and R2 together are alkylenedioxy;R4 and R5 are the same or different and each represents hydrogen, hydroxyl, amino, halogen, mercapto, alkyl, haloalkyl, alkoxy, alkoxycarbonyl or alkylthio;X represents hydrogen, hydroxyl, halogen, alkoxy or haloalkoxy; andY represents an optionally substituted alkyl, cycloalkyl, heterocyclyl, aryl, cycloalkylalkyl, heterocyclylalkyl or aralkyl group.

Alkyl 5,6-dichloro-3,4-dihydro-2(1H)-iminoquinazoline-3-acetate hydrohalides

The known blood platelet antiaggregative agent 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin-2(3H)-one is prepared in high yield via an improved process involving a novel intermediate of the Formula STR1 in which R1 is (lower)alkyl and X is bromo, chloro or iodo. Two processes for the preparation of compounds of the Formula III are disclosed, one of which involves the novel intermediate STR2