207795-41-3Relevant articles and documents
Stereoselective total synthesis of (+)-varitriol
Srinivas,Sridhar,Rao, K. Rama
experimental part, p. 8527 - 8535 (2010/11/18)
Stereoselective total synthesis of (+)-varitriol, an antitumor natural product, was accomplished by two versatile strategies starting from the commercially available d-(-)-ribose and ethyl (S)-lactate. The key steps involved in the synthesis of the target molecule are epoxidation, cyclization, dihydroxylation and Diels-Alder reaction.
Synthesis of the EF-ring segment of ciguatoxin CTX1B based on novel regioselective reduction of unsaturated cyanohydrins and ring-closing olefin metathesis
Takemura, Atsushi,Fujiwara, Kenshu,Shimawaki, Ken,Murai, Akio,Kawai, Hidetoshi,Suzuki, Takanori
, p. 7392 - 7419 (2007/10/03)
Aiming at a convergent total synthesis of ciguatoxin CTX1B, its EF-ring segment has been synthesized. During the synthesis, a novel method for the construction of branched ethers, based on regioselective reduction of γ-alkoxy β,γ-unsaturated α-silyloxy ni
Triphenylphosphine-mediated reduction of electron-deficient propargyl ethers to the allylic ethers
Tsai, Ming-Shan,Rao, U. Narasimha,Wang, Jeng-Rong,Liang, Chung-Hao,Yeh, Ming-Chang P.
, p. 869 - 876 (2007/10/03)
Semihydrogenation of α,β-unsaturated ynoates and -ynones bearing a γ-alkoxy group can be performed using triphenylphosphine and water. α,β-Unsaturated ynoates were reduced to a mixture of cis and trans α,β-unsaturated enoates, whereas, ynones were reduced to trans α,β-unsaturated enones as the only products.
