2078-19-5

Basic information

• Product Name: α-(Trimethylsilyloxy)phenylacetic acid trimethylsilyl ester
• Synonyms: α-(Trimethylsilyloxy)phenylacetic acid trimethylsilyl ester
• CAS NO: 2078-19-5
• Molecular Formula: C₁₄H₂₄O₃Si₂
• Molecular Weight: 296.50956
• Mol File: 2078-19-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: α-(Trimethylsilyloxy)phenylacetic acid trimethylsilyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: α-(Trimethylsilyloxy)phenylacetic acid trimethylsilyl ester(2078-19-5)
• EPA Substance Registry System: α-(Trimethylsilyloxy)phenylacetic acid trimethylsilyl ester(2078-19-5)

Safety Data

• Hazardous Substances Data: 2078-19-5(Hazardous Substances Data)

Upstream product

• 611-71-2 MANDELIC ACID 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 6454-27-9 2-methyl-5-phenyl-[1,3]dioxolan-4-one 
• 343953-13-9 2-Methoxy-2-oxo-5-phenyl-2λ⁵-[1,3,2]dioxaphospholan-4-one 
• 666835-66-1 Cis-(2S,5S)-2-(tert-butyl)-5-phenyl-1,3-dioxolan-4-one 
• 81036-97-7 trans-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one 
• 81036-97-7 cis-2-tert-butyl-5-phenyl-1,3-dioxolan-4-one 

Relevant articles and documents

Synthesis of trimethylsilyl carboxylates by HMDS under solvent-free conditions

A broad set of structurally different carboxylic acids were transformed into their trimethylsilyl esters with HMDS in a practically completely solvent-free process, while a catalytic amount of iodine was required in some cases. The process has several advantages over the known methods: untreated reactants, air atmosphere, mild and neutral conditions, no evolution of hydrogen halide, no need of an additional base, low amount of waste, completely without chromatography, low consumption of energy, and operational simplicity.

Preparation of 5-Alkyl-2-tert-butyl-1,3-dioxolan-4-ones by Trimethylsilyl Triflate Catalyzed Reactions between Bis(trimethylsilyl) Derivatives of α-Hydroxy Carboxylic acids and Pivaldehyde

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