20803-96-7Relevant academic research and scientific papers
Ni/Ir-Catalyzed Photoredox Decarboxylative Coupling of S-Substituted Thiolactic Acids with Heteroaryl Bromides: Short Synthesis of Sulfoxaflor and Its SF5 Analog
Kanishchev, Oleksandr S.,Dolbier, William R.
supporting information, p. 7677 - 7681 (2017/06/06)
Metallaphotoredox cross-coupling reactions have recently emerged as a powerful tool for the construction of C(sp2)?C(sp3) bonds between alkyl chains and aromatic systems, including electron-deficient heteroaryls, which are known to be challenging coupling partners. In this article, we disclose the Ni/Ir-catalyzed photoredox decarboxylative coupling of readily available S-substituted thiolactic acids with electron-deficient heteroaryl bromides, which resulted in the formation of simple but otherwise not easily accessible heteroarenes with alkylsulfide side chains. To demonstrate a practical use of this coupling reaction, we have shown its efficiency in the one-step synthesis of a key intermediate in the synthesis of the recently marketed insecticide Sulfoxaflor, and for the short synthesis of SF5-Sulfoxaflor.
Simple and efficient oxidation of sulfides to sulfones using catalytic ruthenium tetroxide
Rodriguez, Carmen Ma,Ode, Jesus M.,Palazon, Jose Ma,Martin, Victor S.
, p. 3571 - 3576 (2007/10/02)
A procedure for the oxidation of sulfides to sulfones using ruthenium tetroxide as catalyst and periodic acid as stoichiometric oxidant in a biphasic system (CCl4, CH3CN, H2O) is reported.
SYNTHESIS OF 2-ARYLSULFONYLISOVALERIC ACIDS
Polanski, Jaroslaw,Ratajczak, Aleksander
, p. 1973 - 1977 (2007/10/02)
Following the rules of a systematic QSAR study aimed at designing new, more potent sweeteners, the synthesis of 2-arylsulfonylisovaleric acids was carried out.
