20816-79-9

Basic information

• Product Name: 1-Bromo-8-chloronaphthalene
• Synonyms: 1-Bromo-8-chloronaphthalene
• CAS NO: 20816-79-9
• Molecular Formula: C₁₀H₆BrCl
• Molecular Weight: 241.51164
• Mol File: 20816-79-9.mol
• Article Data: 7

Chemical Properties

• Melting Point: 87-88 °C
• Boiling Point: 150-160 °C(Press: 5-6 Torr)
• Appearance: /
• Density: 1.592±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-Bromo-8-chloronaphthalene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Bromo-8-chloronaphthalene(20816-79-9)
• EPA Substance Registry System: 1-Bromo-8-chloronaphthalene(20816-79-9)

Safety Data

• Hazardous Substances Data: 20816-79-9(Hazardous Substances Data)

Usage

Uses

1-Bromo-8-chloronaphthalene is a useful reagent in the preparation of peri-substituted naphthalene series.

Upstream product

• 7647-01-0 hydrogenchloride 
• 145-74-4 8-chloronaphthalene-1-sulfonic acid 
• 7726-95-6 bromine 
• 479-27-6 naphthalene-1,8-diamine 
• 204-03-5 1H-naphtho[1,8-de][1,2,3]triazine 
• 59107-51-6 8-chloronaphthalen-1-amine 

Relevant articles and documents

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COVALENT RAS INHIBITORS AND USES THEREOF

The disclosure features compounds, or pharmaceutically acceptable salts thereof, alone and in combination with other therapeutic agents, pharmaceutical compositions, and protein conjugates thereof, capable of modulating biological processes including Ras, and their uses in the treatment of cancers.

KRAS G12C INHIBITORS

The present invention relates to compounds that inhibit KRas G12C. In particular, the present invention relates to compounds that irreversibly inhibit the activity of KRas G12C, pharmaceutical compositions comprising the compounds and methods of use therefor.