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Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 1192-37-6 methylenecyclohexane 
• 591-49-1 1-methylcyclohex-1-ene 

Relevant academic research and scientific papers

Dynamic asymmetric catalysis by diphenylphosphinoferrocene (DPPF)-nickel complexes through control of axial chirality by chiral diamines

(matrix presented) The enantio- and diastereomerically pure metal complexes of a chirally dynamic diphenylphosphinoferrocene (DPPF) ligand are obtained through coordination of enantiopure diaminobinaphthyl (DABN) to control the axial chirality of DPPF-Pt,

Electron-poor benzonitriles as labile, stabilizing ligands in asymmetric catalysis.

[structure: see text] A chiral palladium catalyst [(S)-MeObiphep)Pd(NCAr)2(SbF6)2, (S)-4c], has been developed for a variety of asymmetric transformations. (S)-4c is bench-stable and has activity comparable to that of the nitrile free Lewis acid catalyst

Heterogeneous enantioselective catalyzed carbonyl- and imino-ene reactions using copper bis(oxazoline) zeolite Y

A recovery discovery: A simple pathway for the synthesis of α-hydroxy and α-amino carbonyl compounds with good yields and high enantioselection is provided by the first heterogeneously catalyzed enantioselective carbonyl-ene and imino-ene reactions. The c

Reversal in enantioselectivity of tert-butyl versus phenyl-substituted bis(oxazoline) copper(II) catalyzed hetero Diels-Alder and ene reactions. Crystallographic and mechanistic studies

X-Ray crystal structures of the Cu[(S,S)-tert-Bu- bis(oxazoline)](H2O)2(SbF6)2 (6), Cu[(S,S)-Ph- bis(oxazoline)](H2O)2(SbF6)2 (7), and Cu[(S,S)-iso-Pr- bis(oxazoline)](H2O)2(SbF6)2 (8) complexes are presented. Implications of the structural details are considered in the context of the opposite enantiofacial biases conferred by complexes Cu[(S,S)-tert-Bu- bis(oxazoline)](x)2 (1, X = OTf or SbF6) and Cu[(S,S)-Ph- bis(oxazoline)](X)2 (2) in hetero Diels-Alder and glyoxytate ene reactions. Structural and mechanistic studies suggest that a change in geometry at the metal center is not necessarily responsible for the reversal in enantioselectivity.

Helical Chirality Control of Palladium Complexes That Bear a Tetrakis(phosphanyl)terphenyl Ligand: Application as Asymmetric Lewis Acid Catalysts

Both axial and helical chirality are generated by complexation of the novel tetrakis(phosphanyl)terphenyl (tetraphos) ligand to a metal center (see picture). The tropos nature of the ligand was confirmed, and enantiopure Pd complexes controlled by diamines were applied as asymmetric Lewis acid catalysts in carbonyl-ene reactions.

Quasi Solvent-Free Enantioselective Carbonyl-Ene Reaction with Extremely Low Catalyst Loading

Simply mixing the neat substrates and a small amount of the chiral catalyst (0.1-0.01 mol%) under nearly solvent-free conditions makes the enantioselective carbonyl-ene reaction of glyoxylate ester with a variety of olefins proceed smoothly to afford the

Highly enantioselective carbonyl-ene reactions catalyzed by a hindered silyl-salen-cobalt complex

We report here the enantioselective carbonyl-ene reactions of various 1,1-disubstituted and trisubstituted alkenes with ethyl glyoxylate. The reactions are catalyzed by a new Co-salen complex, in which bulky triisobutylsilyl (TIBS) substituents occupy the

Chiral palladium(II)-catalyzed asymmetric glyoxylate-ene reaction: Alternative approach to the enantioselective synthesis of α-hydroxy esters

(Matrix presented) An effective chiral palladium catalyst [Pd(CH3CN)2(S)-Tol-BINAP](SbF6)2 (2b) is developed for asymmetric glyoxylate-ene reactions. This palladium dicationic catalyst provides a simple but effi

Electrostatically immobilised BOX and PYBOX metal catalysts: application to ene reactions

Copper(I), copper(II) and scandium(III) triflate complexes of BOX and PYBOX ligands have been electrostatically immobilised on silica. The performance of the immobilised catalysts, in the two carbonyl-ene reactions studied, compares very well with that of

Asymmetric Pt(II)-catalyzed ene reactions: counterion-dependent additive and diphosphine electronic effects.

[reaction: see text]. Catalysis of the glyoxylate-ene reaction by dicationic P2Pt(II) complexes is subject to anion-dependent additive effects. For [((S)-MeOBiphep)Pt](OTf)2 catalysts, acidic phenols such as 3-CF3-C6H3OH or C6F5OH provide substantial rate