20846-02-0

Upstream product

• 64-17-5 ethanol 
• 98-58-8 4-bromobenzenesulfonyl chloride 
• 141-52-6 sodium ethanolate 
• 4596-40-1 cyclopentylcarbinyl p-bromobenzenesulfonate 
• 21816-03-5 2-phenyl-2-methylpropyl tosylate 
• 27852-78-4 cyclobutylcarbinyl p-bromobenzenesulfonate 

Downstream Products

• 75-00-3 chloroethane 
• 100-41-4 ethylbenzene 
• 138-36-3 p-bromobenzene sulfonic acid 
• 3609-87-8 Ν-benzyl-4-bromobenzenesulfonamide 
• 31283-85-9 4-bromo-N-{[(2-methoxyphenyl)amino]carbonyl}benzenesulfonamide 
• 251097-16-2 N-((4-bromophenyl)sulfonyl)proline 
• 834-67-3 4-((4-bromophenyl)sulfonyl)morpholine 

Relevant academic research and scientific papers

SYNTHESIS OF SULFONAMIDE DERIVATIVES

The novel method of synthesis of sulphonamide derivatives (I), comprising reaction of alkyl-4-halophenylsulfonate with an amine. Formula (I) wherein X is halogen and R1 and R2 are independently selected from group comprising (i) C1 to C15 alkyl, straight or branched, (ii) C3 to C15 cycloalkyl, substituted or unsubstituted, (iii) C2 to C15 alkenyl, straight or branched, (iv) C2 to C15 alkynyl, straight or branched, (v) phenyl or benzyl, substituted or unsubstituted, (vi) heterocycloalkyl, substituted or unsubstituted, (vii) hydrogen, (viii) form with the nitrogen to which they are attached a 3-7 membered heterocyclic moiety such as pyrolidine, piperidine, piperazine, imidazole, pyrazole, (ix) the alkyl in i) may be attached to a moiety selected from cycloalkyl or heterocycloalkyl, substituted or unsubstituted