20857-28-7Relevant articles and documents
Metal-free chemo- and regioselective acylation of pyridine derivatives with alcohols in water
Kianmehr, Ebrahim,Pakbaznia, Azin,Faghih, Nasser,Foroumadi, Alireza
, p. 1407 - 1412 (2017/02/18)
A straightforward acylaltion of pyridine derivatives has been developed using K2S2O8as the oxidant and water as a green solvent. The corresponding 2-acylpyridines were synthesized with high chemo- and regioselectivity in good to high yields. This efficient and practical method could serve as a new tool for the convenient synthesis of 2-benzoylpyridines of interest for future pharmaceutical and chemical applications.