20905-98-0

Basic information

• Product Name: 3-(3-Thienyl)-1-propanol
• Synonyms: 3-(3-Thienyl)-1-propanol;3-Thiophenepropanol
• CAS NO: 20905-98-0
• Molecular Formula: C₇H₁₀OS
• Molecular Weight: 142.2187
• Mol File: 20905-98-0.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 244.5±15.0 °C(Predicted)
• Appearance: /
• Density: 1.131±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 15.09±0.10(Predicted)
• CAS DataBase Reference: 3-(3-Thienyl)-1-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3-Thienyl)-1-propanol(20905-98-0)
• EPA Substance Registry System: 3-(3-Thienyl)-1-propanol(20905-98-0)

Safety Data

• Hazardous Substances Data: 20905-98-0(Hazardous Substances Data)

Usage

General Description

3-(3-Thienyl)-1-propanol, also known as 3-(3-thienyl)propan-1-ol, is a chemical compound with the molecular formula C7H10OS. It is a clear, colorless liquid with a thienyl and a hydroxy functional group. 3-(3-Thienyl)-1-propanol is used in a variety of applications, including as a flavor and fragrance ingredient, as well as a chemical intermediate in the synthesis of other organic compounds. It is often used in the production of pharmaceuticals, agrochemicals, and other fine chemicals. Additionally, it is known to have antimicrobial properties, making it useful in the formulation of personal care and cosmetic products. Overall, 3-(3-thienyl)-1-propanol is a versatile chemical with various industrial and commercial uses.

Upstream product

• 33934-92-8 3-(2-propenyl)thiophene 
• 13781-67-4 3-(2-hydroxyethyl)thiophene 
• 21822-40-2 3-(thiophen-3-yl)propanenitrile 
• 1195-52-4 3-(3-thienyl)-2-propenoic acid 
• 50266-60-9 ethyl (2E)-3-(3-thienyl)propenoate 
• 3216-42-0 (E)-3-(thiophen-3-yl)prop-2-en-1-ol 
• 170859-75-3 3-(thiophen-3-yl)prop-2-yn-1-ol 
• 89639-65-6 3-(thien-3-yl)prop-2-en-1-ol 
• 7136-58-5 2-(3'-thienyl)ethyl chloride 
• 26415-26-9 [3]thienylmethyl-malonic acid 
• 26415-25-8 3-thiophen-3-yl methyl malonic acid diethyl ester 
• 616-44-4 3-Methylthiophene 
• 34846-44-1 3-Bromomethylthiophene 
• 50266-60-9 (E)-3-thiophen-3-yl-acrylic acid ethyl ester 

Downstream Products

• 1235541-99-7 (5R,7R)-4,5,6,7-tetrahydro-7-phenylbenzo[b]thiophene-5-carbaldehyde 
• 1235542-36-5 (5R,7S)-4,5,6,7-tetrahydro-7-phenylbenzo[b]thiophene-5-carbaldehyde 
• 1331771-34-6 3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)thiophene 
• 1346260-31-8 C₃₆H₅₀O₂S₂ 
• 128426-57-3 3-(3'-thienyl)propyl toluene-p-sulphonate 

Relevant articles and documents

New spiropyrans and two spirooxazines compounds with one or two thiophene nuclei. Applications to anticopying protection materials

The strategy of synthesis of new thiophene-substituted spiroheterocyclic photochromic structures, in spiropyran or spirooxazine series is described. The polymerization of thiophene entity give interesting semi-conductor systems. Such molecular materials prevent the reproduction of documents and could be useful in other applications such as fast optical switches.

Charge Trapping by Anionic Quinones Electrostatically Bound to a Highly Charged Cationic Quinone-Viologen Polymer or a Cationic Poly(3-viologen-thiophene)

Charge associated with quinone reduction is trapped at low pH in systems composed of sulfonated anthraquinones electrostatically bound to a polymer derived from a monomer consisting of a quinone unit flanked by two viologen units.Each monomer repeat unit carriers 6 equiv of positive charge which can be charge compensated by monosulfonated anthraquinone to yield a quinone:viologen ratio of nearly 7:2.At low pH, electrostatic binding is persistent, and the amount of trapped charge is 90percent of the theoretical maximum.Some of the electrostatically bound quinone can be replaced with Fe(CN)6(3-) to allow mediated release of trapped charge via the Fe(CN)6(3-/4-) redox couple.I(-) is blocked from entering the polymer and thus does not mediate release of charge.Electrostatic binding of anionic quinones to a thiophene polymer with pendant viologen units has also demonstrated.This polymer system has the unique property of having built-in mediators for both the reduction (charge trapping) and oxidation (charge release) of the electrostatically bound anthraquinone.

Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia

Ulotaront (SEP-363856) is a trace-amine associated receptor 1 (TAAR1) agonist with 5-HT1A receptor agonist activity in Phase 3 clinical development, with FDA Breakthrough Therapy Designation, for the treatment of schizophrenia. TAAR1 is a G-protein-coupled receptor (GPCR) that is expressed in cortical, limbic, and midbrain monoaminergic regions. It is activated by endogenous trace amines, and is believed to play an important role in modulating dopaminergic, serotonergic, and glutamatergic circuitry. TAAR1 agonism data are reported herein for ulotaront and its analogues in comparison to endogenous TAAR1 agonists. In addition, a human TAAR1 homology model was built around ulotaront to identify key interactions and attempt to better understand the scaffold-specific TAAR1 agonism structure-activity relationships.

NOVEL PRENYLARENE COMPOUND AND USE THEREOF

A compound represented by the general formula (C): (wherein R101 represents a substituted or unsubstituted aromatic heterocyclic group, R102, R103, R104 and R105 may be the same or different, and each

Enantioselective organo-SOMO cascade cycloadditions: A rapid approach to molecular complexity from simple aldehydes and olefins

A highly selective, radical-mediated (4 + 2) coupling reaction of aldehydes and conjugated olefins has been achieved through asymmetric SOMO-catalysis. A radical-polar crossover mechanism is proposed wherein olefin addition to a transient enamine radical cation and oxidation of the resulting radical furnishes a cation which is vulnerable to nucleophilic addition. A range of aromatic aldehydes are shown to couple with styrenes and dienes to provide cyclic products with high chemical efficiency, regioselectivity, and stereoselectivity.