2093-20-1

Usage

Uses

Used in Paint and Coating Industry:
2-(2-hydroxyethoxy)ethyl acetate is used as a solvent in the paint and coating industry for its high solvency power and low volatility. It helps in creating formulations that dry slowly, providing a longer working time for application and improved finish.
Used in Cleaning Products:
In the cleaning products industry, 2-(2-hydroxyethoxy)ethyl acetate is used as a solvent for its ability to dissolve a wide range of substances. Its low volatility ensures that the cleaning agents remain effective for a longer duration, providing better cleaning performance.
Used as a Safer Alternative to Traditional Solvents:
2-(2-hydroxyethoxy)ethyl acetate is used as a safer alternative to traditional solvents in various applications due to its low toxicity and low odor. This makes it a popular choice for use in enclosed spaces where the use of highly toxic or odoriferous solvents may pose health or comfort risks.

InChI:InChI=1/C6H12O4/c1-6(8)10-5-4-9-3-2-7/h7H,2-5H2,1H3

Upstream product

• 108-24-7 acetic anhydride 
• 111-46-6 diethylene glycol 
• 123-91-1 1,4-dioxane 
• 64-19-7 acetic acid 
• 75-64-9 tert-butylamine 

Downstream Products

• 52452-10-5 4-[2-(2-Acetoxy-ethoxy)-ethoxy]-2-oxo-6-p-tolyl-cyclohex-3-enecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

Self-assembled orthoester cryptands: Orthoester scope, post-functionalization, kinetic locking and tunable degradation kinetics

Dynamic adaptability and biodegradability are key features of functional, 21st century host-guest systems. We have recently discovered a class of tripodal supramolecular hosts, in which two orthoesters act as constitutionally dynamic bridgeheads. Having previously demonstrated the adaptive nature of these hosts, we now report the synthesis and characterization-including eight solid state structures-of a diverse set of orthoester cages, which provides evidence for the broad scope of this new host class. With the same set of compounds, we demonstrated that the rates of orthoester exchange and hydrolysis can be tuned over a remarkably wide range, from rapid hydrolysis at pH 8 to nearly inert at pH 1, and that the Taft parameter of the orthoester substituent allows an adequate prediction of the reaction kinetics. Moreover, the synthesis of an alkyne-capped cryptand enabled the post-functionalization of orthoester cryptands by Sonogashira and CuAAC "click" reactions. The methylation of the resulting triazole furnished a cryptate that was kinetically inert towards orthoester exchange and hydrolysis at pH > 1, which is equivalent to the "turnoff" of constitutionally dynamic imines by means of reduction. These findings indicate that orthoester cages may be more broadly useful than anticipated, e.g. as drug delivery agents with precisely tunable biodegradability or, thanks to the kinetic locking strategy, as ion sensors.

Synthesis of acid-sensitive connection unit and its use in DNA sequencing

The invention discloses a synthesis method of an acid sensitive connection unit, and a use of the acid sensitive connection unit in DNA sequencing. The structural formula of the acid sensitive connection unit is shown in the specification. In the structural formula, R is NH2 or N3, m is an integer from 0 to 44, and n is an integer from 0 to 44; R1 and R2 respectively represent an aliphatic alkyl group, or R1 and R2 respectively represent an aromatic derivative, or R1 is a phenyl group, a naphthyl group, a phenyl derivative or a naphthyl derivative, and R2 is an aliphatic alkyl group or hydrogen; or R2 is a phenyl group, naphthyl group, a phenyl derivative or a naphthyl derivative, R1 is an aliphatic alkyl group or hydrogen, or R1 and R2 form a cyclohexyl group, a cyclopentyl group or a cyclobutyl group. A reversible terminal obtained through connecting the acid sensitive connection unit with nucleotide and fluorescein can be used in DNA sequencing-by-synthesis. The reversible terminal can be used in the DNA sequencing; and raw materials required by the synthesis method are simple and can be easily obtained, and the synthesis process is a routine chemical reaction, so the method can realize large scale popularization use.

Method of Synthesizing Polyol Acetate by Using Catalyst of Ionic Liquid Heteropoly Acid

The present invention uses a nitrogen-containing organic compound to be reacted with an alkyl sultone to obtain a zwitterion compound. The zwitterion compound is reacted with a heteropoly acid (HPA) to obtain an ionic liquid HPA (IL-HPA). The IL-HPA is used for acetylation of polyol and HOAc for obtaining polyol acetate. The IL used in the reaction can be recycled. Thus, problems of product separation, waste acid handling, and corrosion of facilities are solved and production through esterification is improved with a green catalysis.

Synthesis of Sterically Hindered Secondary Aminoether Alcohols

Severely sterically hindered secondary aminoether alcohols are prepared by reacting an organic carboxylic acid or alkali metal salt of an organic carboxylic acid with a sulfonyl halide, a sulfuryl halide, a mixed sulfuryl ester halide or a mixed sulfuryl amide halide to yield a sulfonic-carboxylic anhydride compound which is then reacted with a dioxane to cleave the ring of the dioxane, yielding a cleavage product which cleavage product is then aminated with an alkylamine and hydrolyzed with base to yield the severely sterically hindered secondary aminoether alcohol.

SYNTHESIS OF SEVERELY STERICALLY HINDERED SECONDARY AMINOETHER ALCOHOLS FROM A KETENE AND/OR CARBOXYLIC ACID HALIDE AND/OR CARBOXYLIC ACID ANHYDRIDE

Severely sterically hindered secondary aminoether alcohols are prepared by a process comprising reacting a ketene with sulfuric acid to produce an anhydride which is then reacted with, to cleave the ring of, a dioxane to yield a cleavage product which is then aminated using an amine, followed by hydrolysis with a base to yield the desired severely sterically hindered secondary aminoether alcohol.