20934-51-4

Basic information

• Product Name: 2,3-Quinoxalinedione,1,4-dihydro-1-methyl-(6CI,7CI,9CI)
• Synonyms: 2,3-Quinoxalinedione,1,4-dihydro-1-methyl-(6CI,7CI,9CI);1-METHYL-1,4-DIHYDROQUINOXALINE-2,3-DIONE;1-methyl-1,4-dihydro-2,3-quinoxalinedione(SALTDATA: FREE);1-Methylquinoxaline-2,3(1H,4H)-dione;1,2,3,4-Tetrahydro-1-methyl-2,3-dioxoquinoxaline;4-methyl-1H-quinoxaline-2,3-dione;4-methyl-1H-quinoxaline-2,3-quinone;2,3-Quinoxalinedione, 1,4-dihydro-1-methyl-
• CAS NO: 20934-51-4
• Molecular Formula: C₉H₈N₂O₂
• Molecular Weight: 176.17
• Product Categories: PIPERIDINE
• Mol File: 20934-51-4.mol
• Article Data: 14

Chemical Properties

• Melting Point: 281-283 °C
• Appearance: /
• Density: 1.292g/cm³
• Refractive Index: 1.585
• PKA: 10.23±0.20(Predicted)
• CAS DataBase Reference: 2,3-Quinoxalinedione,1,4-dihydro-1-methyl-(6CI,7CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-Quinoxalinedione,1,4-dihydro-1-methyl-(6CI,7CI,9CI)(20934-51-4)
• EPA Substance Registry System: 2,3-Quinoxalinedione,1,4-dihydro-1-methyl-(6CI,7CI,9CI)(20934-51-4)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• Hazardous Substances Data: 20934-51-4(Hazardous Substances Data)

Usage

General Description

2,3-Quinoxalinedione, 1,4-dihydro-1-methyl is a chemical compound with a molecular formula C9H8N2O2. It is a derivative of quinoxaline and exists as a crystalline solid at room temperature. 2,3-Quinoxalinedione,1,4-dihydro-1-methyl-(6CI,7CI,9CI) is used in organic synthesis and as a building block for the production of other chemicals. It has potential applications in the pharmaceutical industry and as an intermediate for the synthesis of various drugs. Additionally, it may have biological activity and is of interest for further research and development.

InChI:InChI=1/C9H8N2O2/c1-11-7-5-3-2-4-6(7)10-8(12)9(11)13/h2-5H,1H3,(H,10,12)

Upstream product

• 1196-57-2 quinoxalin-2⁽¹⁾-one 
• 6479-18-1 1-methyl-2(1H)-quinoxalinone 
• 95-54-5 1,2-diamino-benzene 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 4732-69-8 Chloro-oxo-acetic acid 
• 4760-34-3 N-methyl-1,2-phenylenediamine 
• 612-28-2 2-nitro-N-methylaniline 
• 4755-77-5 Ethyl oxalyl chloride 
• 79-37-8 oxalyl dichloride 
• 80310-02-7 1-carboxymethyl-1,2,3,4-tetrahydroquinoxaline-3-one 
• 95-92-1 oxalic acid diethyl ester 
• 144-62-7 oxalic acid 

Downstream Products

• 31595-64-9 3-Hydrazino-1-methylchinoxalin-2(1H)on 
• 860503-54-4 1-methyl-3-phenoxy-1H-quinoxalin-2-one 
• 55686-67-4 1-methyl-3-piperazin-1-yl-1H-quinoxalin-2-one 
• 58175-07-8 1,4-dimethylquinoxaline-2,3(1H,4H)-dione 
• 857089-75-9 4-(4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-ylamino)-benzoic acid methyl ester 
• 869199-05-3 4-[methyl-(4-methyl-3-oxo-3,4-dihydro-quinoxalin-2-yl)-amino]-benzoic acid methyl ester 
• 857089-85-1 3-(4-amino-phenylamino)-1-methyl-1H-quinoxalin-2-one 
• 869199-22-4 3-(3-amino-phenylamino)-1-methyl-1H-quinoxalin-2-one 
• 857089-92-0 3-(4-iodo-phenylamino)-1-methyl-1H-quinoxalin-2-one 
• 80708-30-1 1-Oxo-5-methyl-1H,4H(1,2,4)triazolo(4,3-a)quinoxalin-4-one 

Relevant articles and documents

Organic photoredox catalyzed C-H silylation of quinoxalinones or electron-deficient heteroarenes under ambient air conditions

Direct C-H silylation of quinoxalinones was achieved by the combination of organic photoredox catalysis and hydrogen atom transfer (HAT) under ambient air conditions. Transition metal- and external oxidant-free conditions were the major features of this protocol. A series of silylated quinoxalinones with broad functional groups had been synthesized in moderate to high yields. This methodology was also applicable for the C-H silylation of some electron-deficient heteroarenes.

-

-

K2S2O8-catalyzed highly regioselective amidoalkylation of diverse N-heteroaromatics in water under visible light irradiation

A K2S2O8-catalyzed versatile C(sp2)-C(sp3) bond formation with N-heteroaromatics and γ-lactams/amides was developed. Quinoxalin-2(1H)-one, quinoline, isoquinoline, phthalazine, and benzothiazole reacted with γ-lactams/amides to give the corresponding C(sp2)-H amidoalkylation products in moderate to good yields with high regioselectivity. This visible-light-induced photocatalyst-free reaction was conducted in H2O at ambient temperature, which comply with the principles of "green chemistry". The new K2S2O8 catalytic mechanism was investigated with control experiments.

Metal-Free C3 Hydroxylation of Quinoxalin-2(1H)-ones in Water

A practical protocol for the preparation of quinoxaline-2,3(1H,4H)-diones through direct C(sp2)?H hydroxylation of quinoxalin-2(1H)-ones in recyclable DL-α-Tocopherol methoxypolyethylene glycol succinate solution (2 wt% in water) (TPGS-750-M/H