20970-50-7

Usage

Uses

Used in Pharmaceutical Industry:
1-(1-Methyl-1H-imidazol-5-yl)ethanone serves as a crucial precursor in the synthesis of drugs targeting the central nervous system. Its imidazole ring and methyl group provide a versatile chemical scaffold that can be modified to create a range of bioactive molecules with specific therapeutic effects.
Used in Medicinal Chemistry Research:
In the realm of medicinal chemistry, 1-(1-Methyl-1H-imidazol-5-yl)ethanone is utilized as a building block for the development of new compounds with potential therapeutic benefits. Its unique structure allows for the exploration of novel chemical space and the design of innovative drug candidates that can address unmet medical needs.
Used in Drug Discovery:
1-(1-Methyl-1H-iMidazol-5-yl)ethanone plays a significant role in drug discovery, where it is employed to identify and optimize lead compounds with promising pharmacological properties. Its presence in the molecular structure of potential drug candidates can influence their binding affinity, selectivity, and overall efficacy, making it a valuable tool in the quest for new therapeutic agents.

Upstream product

• 592554-79-5 3-methyl-3H-imidazole-4-carboxylic acid methoxy(methyl)amide 
• 75-16-1 methylmagnesium bromide 
• 616-47-7 1-methyl-1H-imidazole 
• 127-19-5 N,N-dimethyl acetamide 

Downstream Products

• 2552-97-8 Isomacrorin 

Relevant academic research and scientific papers

Augmenting Adaptive Machine Learning with Kinetic Modeling for Reaction Optimization

We combine random sampling and active machine learning (ML) to optimize the synthesis of isomacroin, executing only 3% of all possible Friedl?nder reactions. Employing kinetic modeling, we augment machine intuition by extracting mechanistic knowledge and

Novel farnesyl protein transferase inhibitors as antitumor agents

Disclosed are novel tricyclic compounds represented by the formula (1.0): and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.

Imidazolo-5-YL-2anilino-pyrimidines as agents for the inhibition of the cell proliffration

Compounds of the formula (I): wherein R1, R2, R3, R4, R5, R6, p, q, and n are as defined within and a pharmaceutically acceptable salts and in vivo hydrolysable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-blooded animal, such as man.