209900-64-1

Basic information

• Product Name: (S)-3-phenyl-4-pentenoic acid
• Synonyms: (S)-3-phenyl-4-pentenoic acid
• CAS NO: 209900-64-1
• Molecular Weight: 176.215
• Mol File: 209900-64-1.mol

Chemical Properties

• CAS DataBase Reference: (S)-3-phenyl-4-pentenoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-phenyl-4-pentenoic acid(209900-64-1)
• EPA Substance Registry System: (S)-3-phenyl-4-pentenoic acid(209900-64-1)

Safety Data

• Hazardous Substances Data: 209900-64-1(Hazardous Substances Data)

Upstream product

• 100556-66-9 3-phenylpent-4-enoic acid amide 
• 137586-02-8 3-Phenyl-pent-4-enoyl chloride 
• 90172-86-4 methyl 3-phenyl-4-pentenoate 
• 60066-61-7 ethyl 3-phenyl-4-pentenoate 
• 104-54-1 3-Phenylpropenol 
• 5703-57-1 3-phenylpent-4-enoic acid 
• 132769-61-0 3-phenyl-pent-4-ene nitrile 
• 918149-64-1 (S)-(-)-3-phenyl-4-pentenamide 

Downstream Products

• 209900-68-5 (4R,5R)-5-Iodomethyl-4-phenyl-dihydro-furan-2-one 
• 209900-66-3 (4R,5S)-5-Iodomethyl-4-phenyl-dihydro-furan-2-one 
• 918149-86-7 (S)-(+)-N-allyl-N-benzyl-3-phenyl-4-pentenamide 
• 5669-17-0 (R) 3-phenylvaleric acid 
• 5703-57-1 3-phenylpent-4-enoic acid 

Relevant articles and documents

The studies on chemoenzymatic synthesis of Femoxetine

The studies on enzymatic kinetic resolution of 3-phenyl-4-pentenoic acid esters were performed. The obtained results demonstrated that the careful choice of biocatalyst and a reaction type are very important for successful enzymatic kinetic resolution. Ki

An unusual β-vinyl effect leading to high efficiency and enantioselectivity of the amidase, nitrile biotransformations for the preparation of enantiopure 3-arylpent-4-enoic acids and amides and their applications in synthesis

(Chemical Equation Presented) Biotransformations of 3-arylpent-4- enenitriles catalyzed by Rhodococcus erythropolis AJ270, a nitrile hydratase/amidase-containing microbial whole-cell catalyst were studied, and an unusual β-vinyl effect of the substrate on

Synthesis of versatile chiral intermediates by enantioselective conjugate addition of alkenyl Grignard reagents to enamides deriving from (R)-(-)- or (S)-(+)-2-aminobutan-1-ol

Conjugate addition of but-3-enylmagnesium bromide to the chiral crotonamide (R)-(+)- and (S)-(-)-3, followed by hydrolysis and oxidation, afforded enantiopure (R)-(+)- and (S)-(-)-3-methyladipic acids 8, respectively. Conjugate addition of vinylmagnesium chloride to the chiral crotonamide and cinnamamides (R)-(+)-3-5, followed by hydrolysis, gave the alkenoic acids (S)-12-14, respectively. Iodolactonization of the latter led to the 5-iodomethyllactones (+)-15-17, which were reduced by means of n- Bu3SnH into the trans-disubstituted 5-methyllactones (+)-19-21, respectively. Treatment of the iodomethyllactone (+)-16 with LiMe2Cu or n- Bu2CuLi furnished the trans-5-alkyl-4-phenyllactones (-)-22 or (+)-23.