210229-40-6Relevant academic research and scientific papers
A Convergent Total Synthesis of the Biologically Active Benzofurans Ailanthoidol, Egonol and Homoegonol from Biomass-Derived Eugenol
Espinoza-Hicks, José C.,Zaragoza-Galán, Gerardo,Chávez-Flores, David,Ramos-Sánchez, Víctor H.,Tamariz, Joaquín,Camacho-Dávila, Alejandro A.
, p. 3493 - 3498 (2018)
An efficient, general synthetic protocol for the synthesis of the biologically active benzofurans ailanthoidol, egonol and homoegonol was developed. The key starting material, eugenol, is a naturally occurring and abundant precursor. The protocol, involving sequential acylation and intramolecular Wittig reaction, provides a convenient method for building the benzofuran moiety in good yield.
Synthesis of Naturally Occuring 5-Allyl-2-aryl-7-methoxybenzofurans and 2-Aryl-5-(3-hydroxypropyl)-7-methoxybenzofurans
Mali, Raghao S.,Massey, Archna Patience
, p. 1109 - 1120 (2007/10/03)
A convenient and general procedure is described for the synthesis of 5-allyl-2-aryl-7-methoxybenzofurans (8a-e) from 2-allyloxy-3-methoxybenzaldehyde (3).The compounds 8a and 8b on hydraboration followed by oxidation provide the naturally occuring benzofurans (1a and 1b)
