2105-59-1

Usage

Uses

Used in Pharmaceutical Industry:
2,4-Dichloro-5-fluoronitrobenzene is used as an intermediate in the synthesis of pharmaceuticals for its versatile chemical properties, enabling the production of various medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical sector, 2,4-Dichloro-5-fluoronitrobenzene serves as a key intermediate, contributing to the development of effective crop protection agents and other agricultural products.
Used in Organic Synthesis:
2,4-Dichloro-5-fluoronitrobenzene is utilized as a building block in organic synthesis, particularly in the production of dyes and other specialty chemicals, due to its unique molecular structure and reactivity.
Used in Chemical Research:
2,4-Dichloro-5-fluoronitrobenzene is also employed in chemical research for studying reaction mechanisms and exploring new synthetic pathways, further expanding its applications in the field of chemistry.

Upstream product

• 1435-48-9 1,3-dichloro-4-fluorobenzene 

Downstream Products

• 104222-36-8 3-bromo-2,4-dichloro-5-fluoronitrobenzene 
• 2105-61-5 1,2,4-trifluoro-5-nitrobenzene 
• 1025506-84-6 (R)-4-chloro-N-(1-(6-chloro-1-ethyl-5-fluoro-1H-benzo[d]imidazol-2-yl)ethyl)benzenesulfonamide 
• 1025509-54-9 4-chloro-N₂-ethyl-5-fluoro-benzene-1,2-diamine 
• 1025509-24-3 [(R)-1-(4-chloro-2-ethylamino-5-fluoro-phenylcarbamoyl)-ethyl]-carbamic acid tert-butyl ester 
• 958031-75-9 2,4-dichloro-5-[(2,2,2-trifluoroethyl)thio]aniline 
• 958031-89-5 2-(2,4-dichloro-5-fluorophenyl)-1H-isoindol-1,3(2H)-dione 
• 958031-90-8 2-{2,4-dichloro-5-[(2,2,2-trifluoroethyl)thio]phenyl}-1H-isoindol-1,3(2H)-dione 
• 2367-78-4 5-chloro-1,2,4-trifluorobenzene 
• 209995-38-0 (2,4,5-trifluorophenyl)acetic acid 
• 367-34-0 2,4,5-trifluoroaniline 
• 367-23-7 1,2,4-trifluorobenzene 
• 348-64-1 2,4-dichloro-5-fluoroaniline 

Relevant academic research and scientific papers

2. The preparation method of the 4, 5 - trifluorobenzene acetic acid

The invention discloses a 2, 4, 5 - trifluorobenzene acetic acid preparation method, which belongs to the chemical pharmaceutical intermediates preparation method technical field, the use of 2, 4 - dichlorofluorobenzene as raw materials, by nitration, fluorinated, chlorinated, coupling and hydrolysis reaction for preparing 2, 4, 5 - trifluorobenzene acetic acid. The method of the invention, the raw materials using relatively inexpensive and easy to obtain, the process route is mature, the operation is simple, high yield, and has high industrial value.

Synthetic method for 1,2,4-trifluorobenzene

The invention provides a synthetic method for 1,2,4-trifluorobenzene, belongs to the field of pesticide, medicine, and liquid crystal material intermediate preparation, and solves the problem of harshreaction conditions of a current method for synthesizing 1,2,4-trifluorobenzene. The synthetic method for the 1,2,4-trifluorobenzene is characterized by comprising the following steps: performing nitration by using 2,4-dichlorofluorobenzene as a raw material and nitric acid as a nitrating agent to form 2,4-dichloro-5-fluoronitrobenzene in the presence of sulfuric acid; dissolving the 2,4-dichloro-5-fluoronitrobenzene into an organic solvent, adding potassium fluoride and a first catalyst, and performing fluorination under the catalysis of the first catalyst to obtain 2,4,5-trifluoronitrobenzene; dissolving the 2,4,5-trifluoronitrobenzene into a solvent, and performing hydrogenation reduction with hydrogen under the catalysis of a second catalyst to obtain 2,4,5-trifluoroaniline; and performing a reaction on the 2,4,5-trifluoroaniline and sulfuric acid, after a salt is formed, performing a diazotization reaction on the salt and nitroso-sulfuric acid, performing a deamination reductionreaction with sodium hypophosphite under the catalysis of a copper salt, and finally performing steam distillation to obtain the 1,2,4-trifluorobenzene. The method provided by the invention has the advantages of mild reaction conditions and the like

INSECTICIDAL BENZAMIDINES

Novel benzamidines of the formula (I) and a use thereof as insecticides

Process for preparing a quinolone-carboxylic acid

The present invention provides a process for preparing quinolonecarboxylic acid derivatives having the formula (I): wherein R1 is H, halogen, or amino; R2 is halogen; R3 is H, halogen, C1-4 alkoxyl, or CN; R4 is selected from the group consisting of C3-6cycloalkyl, C1-4alkyl, C1-4alkoxyC1-4alkyl, and C1-4alkylaminoC1-4alkyl. The invention also provides new acetophenones having the formula (II) that are intermediates for preparing the compound of the formula (I).