2367-78-4

Usage

Chemical classification

Chlorofluorocarbon (CFC)

Physical state

Colorless liquid

Solubility

Insoluble in water

Primary use

Intermediate in the production of pharmaceuticals, agrochemicals, and other organic compounds

Chemical structure

Benzene ring with three fluorine atoms and one chlorine atom attached at specific positions (1-chloro-2,4,5-trifluorobenzene)

Stability

Highly stable compound

Reactivity

Low reactivity

Industrial application

Suitable for use in various industrial processes due to its stability and low reactivity

Environmental impact

Potential for contributing to ozone depletion and global warming

Regulation

Use and production are heavily regulated, and its use is being phased out in many countries due to environmental concerns

Upstream product

• 95-94-3 1,2,4,5-tetrachlorobenzene 
• 2105-61-5 1,2,4-trifluoro-5-nitrobenzene 
• 2105-59-1 2,4-dichloro-5-fluoronitrobenzene 
• 1435-48-9 1,3-dichloro-4-fluorobenzene 

Downstream Products

• 367-23-7 1,2,4-trifluorobenzene 

Relevant academic research and scientific papers

'Halex' fluorination of 1,2,4,5-tetrachlorobenzene in a pressure reactor

Halogen exchange of 1,2,4,5-tetrachlorobenzene with spray-dried potassium fluoride has been found to proceed smoothly using 1,3-dimethyl-2-imidazolidinone as a solvent at 300 deg C in a pressure reactor to give 2,4,5-trifluorochlorobenzene without any rearrangement.

2. The preparation method of the 4, 5 - trifluorobenzene acetic acid

The invention discloses a 2, 4, 5 - trifluorobenzene acetic acid preparation method, which belongs to the chemical pharmaceutical intermediates preparation method technical field, the use of 2, 4 - dichlorofluorobenzene as raw materials, by nitration, fluorinated, chlorinated, coupling and hydrolysis reaction for preparing 2, 4, 5 - trifluorobenzene acetic acid. The method of the invention, the raw materials using relatively inexpensive and easy to obtain, the process route is mature, the operation is simple, high yield, and has high industrial value.

Method for producing tetrakis ( fluoroaryl) borate-magnesium compound

Fluoroaryl magnesium halide is reacted with a boron compound so that a molar ratio of the fluoroaryl magnesium halide to the boron compound is not less than 3.0 and not more than 3.7, so as to produce a tetrakis (fluoroaryl) borate·magnesium compound. With this method, there occurs no hydrogen fluoride which corrodes a producing apparatus and requires troublesome waste water treatment.