2109-84-4

Basic information

• Product Name: 1-[(2-methylbut-3-yn-2-yl)oxy]-4-nitrobenzene
• CAS NO: 2109-84-4
• Molecular Formula: C₁₁H₁₁NO₃
• Molecular Weight: 205.2099
• Mol File: 2109-84-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 323.201°C at 760 mmHg
• Flash Point: 142.348°C
• Density: 1.172g/cm³
• Vapor Pressure: 0.001mmHg at 25°C
• Refractive Index: 1.55
• CAS DataBase Reference: 1-[(2-methylbut-3-yn-2-yl)oxy]-4-nitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2-methylbut-3-yn-2-yl)oxy]-4-nitrobenzene(2109-84-4)
• EPA Substance Registry System: 1-[(2-methylbut-3-yn-2-yl)oxy]-4-nitrobenzene(2109-84-4)

Safety Data

• Hazardous Substances Data: 2109-84-4(Hazardous Substances Data)

Usage

Molecular weight

225.21 g/mol

Physical state

Yellow crystalline solid

Chemical properties

a. Ability to undergo nucleophilic substitution reactions
b. Ability to undergo cross-coupling reactions

Applications

a. Starting material in organic synthesis
b. Reagent in chemical reactions
c. Precursor for the synthesis of pharmaceutical compounds

Safety precautions

Toxic if ingested, inhaled, or comes into contact with skin

Upstream product

• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 100-02-7 4-nitro-phenol 
• 19021-53-5 methyl (2-methylbut-3-yn-2-yl)carbonate 
• 61570-79-4 1,1-dimethyl-2-propynyl trifluoroacetate 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 50965-91-8 sodium salt of 1,1-dimethylpropynol 
• 350-46-9 4-Fluoronitrobenzene 
• 905718-45-8 [(4-nitrophenyl)(phenyl)iodonium trifluoromethanesulfonate] 
• 636-98-6 p-nitrobenzene iodide 

Downstream Products

• 33143-28-1 6-nitro-2,2-dimethyl chromene 
• 86824-20-6 (3R,4S)-2,2-Dimethyl-6-nitro-4-(4-phenyl-piperazin-1-yl)-chroman-3-ol 
• 1417919-60-8 (hexacarbonyldicobalt)-2-methyl-3-butyn-2-yl para-nitrophenyl ether 

Relevant articles and documents

Mild synthesis of sterically congested alkyl aryl ethers

An efficient and transition-metal-free method is presented to access tertiary alkyl aryl ethers by arylation of tertiary alcohols with ortho-substituted diaryliodonium salts. The scope covers cyclic and acyclic aliphatic, benzylic, allylic, and propargyli

Anticancer (hexacarbonyldicobalt)propargyl aryl ethers: Synthesis, antiproliferative activity, apoptosis induction, and effect on cellular oxidative stress

While an increasing number of (hexacarbonyldicobalt)alkynes have been found to possess antiproliferative activity against a number of cancer cell lines, the role of the organometallic moiety in this bioactivity is not well understood. To gain a better und

Asymmetric counteranion-directed transition-metal catalysis: Enantioselective epoxidation of alkenes with Manganese(III) salen phosphate complexes

(Figure Presented) Figure Presentation Paired up: A highly active and enantioselective ion-pair epoxidation catalyst, consisting of an achiral Mn |||-salen complex and a chiral phosphate counteranion, mediates the epoxidization of a wide range of alkenes with high yields and enantioselectivities (see scheme). The unique role of the counteranion is to stabilize an enantiomorphic conformation of the cationic Mn catalyst.