210903-90-5Relevant academic research and scientific papers
Novel structural analogs of glyphosate based on azoles. 1. Synthesis of 1H-imidazoles containing carboxyl and phosphoryl groups in the ring
Pavlenko,Oos,Yagupolskii,Van Almsick,Willms
experimental part, p. 36 - 44 (2012/01/03)
A general method has been developed for the synthesis of 1H-imidazoles containing a phosphoryl group in positions 2 or 4(5) based on lithium intermediates. The possibility of further functionalization of the ring using electrophiles has also been demonstrated.
Direct phosphorylation of N-protected imidazoles and benzoimidazoles - A route to 1H-imidazol(benzoimidazol)-2-yl phosphonic and phosphinic acids and their derivatives
Komarov, Igor V.,Strizhak, Aleksandr V.,Kornilov, Mikhail Yu.,Kostyuk, Aleksandr N.,Tolmachev, Andrey A.
, p. 2355 - 2370 (2007/10/03)
Synthetic approaches to 1H-imidazol-2-yl and 1H-benzoimidazol-2-yl phosphinic and phosphonic acids and their derivatives are reported, based on phosphorylation of N-protected heterocylcles by PhPOCl2 or MePOCl2. Reaction of N-alkylbe
