21112-64-1Relevant articles and documents
Deuteration of Aromatic Rings under Very Mild Conditions through Keto-Enamine Tautomeric Amplification
Mehr, S. Hessam M.,Fukuyama, Katsuya,Bishop, Stephanie,Lelj, Francesco,MacLachlan, Mark J.
, p. 5144 - 5150 (2015)
We have discovered a surprising, mild method for deuteration of select aromatic compounds that is facilitated by a keto-enamine tautomeric intermediate. The mechanism of the reaction has been studied using kinetics experiments and detailed computational a