21162-08-3Relevant academic research and scientific papers
Transition metal-free and regioselective vinylation of phosphine oxides and: H -phosphinates with VBX reagents
Castoldi, Laura,Rajkiewicz, Adam A.,Olofsson, Berit
supporting information, p. 14389 - 14392 (2020/12/01)
A series of phosphine oxides and H-phosphinates were vinylated in the presence of the iodine(iii) reagents vinylbenziodoxolones (VBX), providing the corresponding alk-1-enyl phosphine oxides and alk-1-enyl phosphinates in good yields with complete chemo- and regioselectivity. The vinylation proceeds in open flask under mild and transition metal-free conditions.
P-Chiral Phosphines Enabled by Palladium/Xiao-Phos-Catalyzed Asymmetric P-C Cross-Coupling of Secondary Phosphine Oxides and Aryl Bromides
Dai, Qiang,Li, Wenbo,Li, Zhiming,Zhang, Junliang
supporting information, p. 20556 - 20564 (2019/12/27)
The development of transition-metal-catalyzed methods for the synthesis of P-chiral phosphine derivatives poses a considerable challenge. Herein, we present a direct Pd/Xiao-Phos-catalyzed cross-coupling reaction of easily accessible secondary phosphine o
A straightforward synthesis of unsymmetrical secondary phosphine boranes
Petit, Christelle,Favre-Reguillon, Alain,Mignani, Gerard,Lemaire, Marc
, p. 326 - 330 (2011/03/18)
A one-pot procedure for the synthesis of unsymmetrical alkyl-substituted secondary phosphine oxides is described. The sequential addition of N-benzylaniline to a solution of dichlorophenylphosphine and 1-methylimidazole in methylcyclohexane, separating of the protic ionic liquid formed, addition of Grignard reagent followed by hydrolysis gave unsymmetrical secondary phosphine oxides (SPOs) in high yield. The use of ionic liquids in the first step is essential and streamlined the synthesis. Unsymmetrical SPOs could be quantitatively reduced to secondary phosphine using a catalytic amount of Ti(OiPr)4 and tetramethyldisiloxane (TMDS) under mild reaction conditions.
Degradation of (PhP)5 by Cyanide: Formation, Structure, and Reactions of the Phenyl Cyanophosphide Ion
Schmidpeter, Alfred,Zirzow, Karl-Heinz,Burget, Guenther,Huttner, Gottfried,Jibril, Ibrahim
, p. 1695 - 1706 (2007/10/02)
Phenyl cyanophosphide PhPCN- is formed in the ractions of P(CN)2- with phenyllithium and of PhP(CN)2 with CN-, and it may be prepared by nucleophilic degradation of (PhP)5 with ammonium or phosphonium cyanides.With sulfur it yields phenyl cyanodithiophosphinates 4, by alkylation alkyl(phenyl)cyanophosphanes 6 and by hydrolysis of the latter alkyl(phenyl)phosphine oxides 7. - The molecular structure of PhPCN (3c) as determined by X-ray analysis shows an almost planar anion with 102 deg CPC angle.A long PC and short CN bond in the PCN group make PhPCN- appear as "cyanide complex of phenylphosphinidene".
