211676-02-7

Basic information

• Product Name: Benzenesulfonamide, N-methyl-N-(4-methylphenyl)-4-nitro-
• CAS NO: 211676-02-7
• Molecular Formula: C14H14N2O4S
• Molecular Weight: 306.342
• Mol File: 211676-02-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, N-methyl-N-(4-methylphenyl)-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, N-methyl-N-(4-methylphenyl)-4-nitro-(211676-02-7)
• EPA Substance Registry System: Benzenesulfonamide, N-methyl-N-(4-methylphenyl)-4-nitro-(211676-02-7)

Safety Data

• Hazardous Substances Data: 211676-02-7(Hazardous Substances Data)

Upstream product

• 98-74-8 4-Nitrobenzenesulfonyl chloride 
• 99-97-8 Dimethyl-p-toluidine 
• 6319-45-5 N-methyl-4-nitro-benzenesulfonamide 
• 108-88-3 toluene 
• 109845-76-3 4-nitro-N-(p-tolyl)benzenesulfonamide 
• 74-88-4 methyl iodide 

Relevant articles and documents

Nanosized CdS as a Reusable Photocatalyst: The Study of Different Reaction Pathways between Tertiary Amines and Aryl Sulfonyl Chlorides through Visible-Light-Induced N-Dealkylation and C-H Activation Processes

It has been found that the final products of the reaction of sulfonyl chlorides and tertiary amines in the presence of cadmium sulfide nanoparticles under visible light irradiation are highly dependent on the applied reaction conditions. Interestingly, with the change of a reaction condition, different pathways were conducted (visible-light-induced N-dealkylation or sp3 and sp2 C-H activation) that lead to different products such as secondary amines and various sulfonyl compounds. Remarkably, all of these reactions were performed under visible light irradiation and an air atmosphere without any additive or oxidant in benign solvents or under solvent-free conditions. During this study, the CdS nanoparticles as affordable, heterogeneous, and recyclable photocatalysts were designed, successfully synthesized, and fully characterized and applied for these protocols. During these studies, intermediates resulting from the oxidation of tertiary amines are trapped during the photoinduced electron transfer (PET) process. The reaction was carried out efficiently with a variety of substrates to give the corresponding products at relatively short times in good to excellent yields in parallel with the use of the visible light irradiation as a renewable energy source. Most of these processes are novel or are superior in terms of cost-effectiveness, safety, and simplicity to published reports.

Study on Radical Amidation onto Aromatic Rings with (Diacyloxyiodo)arenes

Sulfonamides of primary amines bearing an aromatic ring at the γ-position were treated with (diacyloxyiodo)arenes and iodine under irradiation conditions with a tungsten lamp to give the corresponding 1,2,3,4-tetrahydroquinoline derivatives in moderate to good yields. Here, the reactivity depends on the Z-group (protecting group) of the starting amides. Under the same reaction conditions, some sulfonamides were treated with (diacetoxyiodo)benzene and iodine in the presence of aromatics to give the corresponding N-arylated amides. These reactions proceed through the intramolecular and intermolecular amidations onto aromatic rings via the sulfonamidyl radicals formed.