211945-49-2

Basic information

• Product Name: (R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene
• Synonyms: (R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene
• CAS NO: 211945-49-2
• Molecular Weight: 314.616
• Mol File: 211945-49-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene(211945-49-2)
• EPA Substance Registry System: (R)-2-t-butyldimethylsilyloxymethyl-1-trimethylsilyloxycyclohexene(211945-49-2)

Safety Data

• Hazardous Substances Data: 211945-49-2(Hazardous Substances Data)

Upstream product

• 211945-47-0 (1R,2R)-2-t-butyldimethylsilyloxymethylcyclohexanol 
• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1655-06-7 cis-ethyl 2-hydroxy-cyclohexanoate 
• 187263-73-6 ethyl (1S,2R)-2-acetoxycyclohexanecarboxylate 
• 51606-50-9 (1R,2R)-2-(hydroxymethyl)cyclohexanol 
• 75-77-4 chloro-trimethyl-silane 
• 211945-48-1 (R)-2-t-butyldimethylsilyloxymethylcyclohexanone 

Downstream Products

• 135297-29-9 (3S,4R)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-[(2'R,6'R)-2'-(t-butyldimethylsilyloxymethyl)cyclohexanone-6'-yl]azetidin-2-one 
• 299177-89-2 {(2R,3S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[(1R,3R)-3-(tert-butyl-dimethyl-silanyloxymethyl)-2-oxo-cyclohexyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester 
• 256642-02-1 (3S,4R)-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-4-[(2'R,6'R)-2'-(triethylsilyloxymethyl)cyclohexanone-6'-yl]azetidin-2-one 
• 211945-46-9 (3S,4R)-3-[(R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-[(2R,6R)-2-(hydroxymethyl)cyclohexanon-6-yl]azetidin-2-one 

Relevant articles and documents

Stereoselective synthesis of novel anti-MRSA tricyclic carbapenems (trinems)

(4S)-Hydroxymethyltrinem 3 was prepared via stereoselective aldol-type reaction with optically pure (R)-2-t-butyldimethylsilyloxymethylcyclohexanone ((R)-16). (4S)-Hydroxymethyltrinem 3 was converted into various kinds of trinem derivatives with anti-MRSA activity by using the Mitsunobu reaction. (C) 2000 Elsevier Science Ltd.