212203-90-2Relevant articles and documents
RING CONSTRAINED DIARYLAMINO SULFONAMIDES AS ANTI-CANCER AGENTS
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Paragraph 00197, (2017/03/28)
A genus of arylsulfonamide derivatives of ring constrained diarylamino sulfonamide compounds is disclosed. The compounds are of the following genus:. The compounds induce FOXO1 transcription factor translocation to the nucleus by modulating PP2A and, as a consequence, exhibit anti-proliferative effects. They are useful in the treatment of a variety of disorders, including as a therapy in cancer treatment, or used in combination with other drugs to restore sensitivity to chemotherapy where resistance has developed.
Micellar catalysis using a photochromic surfactant: Application to the pd-catalyzed tsuji-trost reaction in water
Billamboz, Muriel,Mangin, Floriane,Drillaud, Nicolas,Chevrin-Villette, Carole,Banaszak-Leonard, Estelle,Len, Christophe
, p. 493 - 500 (2014/04/03)
The first example of a Pd-catalyzed Tsuji-Trost reaction, applied in a photochromic micellar media under conventional heating and microwave irradiation, is reported. The surfactant activity and recycling ability were investigated and compared with those of a few commercially available surfactants. The synthetic photochromic surfactant proved to be efficient, recyclable, and versatile for Pdcatalyzed coupling reactions.
Synthesis and biological evaluation of selective and potent cyclin-dependent kinase inhibitors
N'Gompaza-Diarra, Joannah,Bettayeb, Karima,Gresh, Nohad,Meijer, Laurent,Oumata, Nassima
, p. 210 - 216 (2013/01/15)
A new series of 2,6,9-trisubstituted purines, structurally related to the cyclin-dependent kinase (CDK) inhibitor Roscovitine, has been synthesized. These compounds mainly differ by the substituent on the C-2 position which encompasses a diol group. These
