21258-32-2

Basic information

• Product Name: propionic acid-(4-iodo-anilide)
• Synonyms: propionic acid-(4-iodo-anilide)
• CAS NO: 21258-32-2
• Molecular Weight: 275.089
• Mol File: 21258-32-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: propionic acid-(4-iodo-anilide)(CAS DataBase Reference)
• NIST Chemistry Reference: propionic acid-(4-iodo-anilide)(21258-32-2)
• EPA Substance Registry System: propionic acid-(4-iodo-anilide)(21258-32-2)

Safety Data

• Hazardous Substances Data: 21258-32-2(Hazardous Substances Data)

Upstream product

• 123-62-6 propionic acid anhydride 
• 540-37-4 p-aminoiodobenzene 
• 622-50-4 4-Acetamido-1-iodobenzene 

Downstream Products

• 642410-36-4 2-bromo-N-(4-iodophenyl)-N-propylacetamide 
• 160127-66-2 4-iodo-N-propylaniline 

Relevant articles and documents

Solid phase approaches to N-heterocycles using a sulfur linker cleaved by SmI2

A sulfur HASC (α-hetero-atom substituted carbonyl) linker has been utilized in solid-phase approaches to oxindoles and tetrahydroquinolones. The route to oxindoles employs the first Pummerer cyclizations on solid phase, whereas the route to tetrahydroquinolones involves a microwave-assisted Heck reaction followed by a Michael cyclization. In both cases, the linker is cleaved in a traceless fashion by electron transfer from samarium(II) iodide. The routes illustrate the compatibility of the linker system with a number of reaction types and its utility for library synthesis.