212890-88-5

Basic information

• Product Name: (S)-(+)-1-aza-3,3-bisbenzyl-8,8-dimethyl-7-oxabicyclo[3.3.0]octan-2-one
• Synonyms: (S)-(+)-1-aza-3,3-bisbenzyl-8,8-dimethyl-7-oxabicyclo[3.3.0]octan-2-one
• CAS NO: 212890-88-5
• Molecular Weight: 335.446
• Mol File: 212890-88-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-(+)-1-aza-3,3-bisbenzyl-8,8-dimethyl-7-oxabicyclo[3.3.0]octan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-1-aza-3,3-bisbenzyl-8,8-dimethyl-7-oxabicyclo[3.3.0]octan-2-one(212890-88-5)
• EPA Substance Registry System: (S)-(+)-1-aza-3,3-bisbenzyl-8,8-dimethyl-7-oxabicyclo[3.3.0]octan-2-one(212890-88-5)

Safety Data

• Hazardous Substances Data: 212890-88-5(Hazardous Substances Data)

Upstream product

• 99208-71-6 (5S)-1-aza-2,2-dimethyl-3-oxa-8-oxo-bicyclo[3.3.0]octane 
• 100-39-0 benzyl bromide 

Downstream Products

• 627503-57-5 (S)-3,3-Dibenzyl-5-[(diphenylphosphanyl)-methyl]-pyrrolidin-2-one 
• 212890-82-9 (S)-(-)-1-[4,4-bisbenzyl-2-((diphenylphosphino)methyl)pyrrolidinyl]-2,2-dimethylpropan-1-one 
• 212890-90-9 (S)-(+)-(4,4-dibenzylpyrrolidin-2-yl)methan-1-ol 
• 950172-24-4 (S)-(+)-(N-benzyloxycarbonyl)-(4,4-dibenzylpyrrolidin-2-yl)methan-1-ol 
• 212890-89-6 (S)-(+)-3,3-bisbenzyl-5-(hydroxymethyl)pyrrolidin-2-one 
• 212890-93-2 (S)-(-)-tert-butyl 4,4-bisbenzyl-2-[(diphenylphosphino)methyl]pyrrolidinecarboxylate 
• 212890-92-1 (S)-(-)-tert-butyl 4,4-bisbenzyl-2-[((4-methylphenyl)sulfonyloxy)methyl]pyrrolidinecarboxylate 
• 212890-91-0 (S)-(-)-tert-butyl 4,4-bisbenzyl-2-(hydroxymethyl)pyrrolidinecarboxylate 

Relevant articles and documents

An external chiral amidophosphine ligand for asymmetric conjugate addition of organocopper

Two types of external, chiral amidophosphine ligands, 1-5, were prepared. Examination of their behavior in an asymmetric conjugate addition reaction of organocuprate revealed the possibility for steric tuning to realize high selectivity.

Asymmetric Alkylation of N-Toluenesulfonylimines with Dialkylzinc Reagents Catalyzed by Copper-Chiral Amidophosphine

The synthetic procedure of a chiral amidophosphine ligand 5 bearing two bulky substituents, 2,4,6-trimethylphenylmethyl or 2,4,6-triisopropylphenylmethyl groups, on the pyrrolidine ring was improved by employing the borane-THF reduction of the lactam-alco