213331-29-4

Upstream product

• 5582-62-7 1-trimethylsilyloxy-2-propyne 
• 100-52-7 benzaldehyde 
• 762-72-1 allyl-trimethyl-silane 
• 107-19-7 propargyl alcohol 
• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 106-96-7 propargyl bromide 
• 624-65-7 2-propynyl chloride 

Downstream Products

• 213331-33-0 (+/-)-2-phenyl-5-vinyl-3,6-dihydro-2H-pyran 

Relevant academic research and scientific papers

Cyclopropanation of Benzene Rings by Oxidatively Generated α-Oxo Gold Carbene: One-Pot Access to Tetrahydropyranone-Fused Cycloheptatrienes from Propargyl Benzyl Ethers

Cyclopropanations of benzene rings by oxidatively generated α-oxo gold carbenes are for the first time demonstrated in a Buchner reaction, in which readily available propargyl benzyl ethers are converted in one-pot to tetrahydropyranone-fused cycloheptatrienes via sequential oxidative gold catalysis and base-promoted isomerization. Additional examples of arene cyclopropanations without fragmentation of the cyclopropane ring are also realized. (Figure presented.).

Total synthesis of 20-norsalvinorin A. 1. Preparation of a key intermediate

The key tricylic intermediate 3a, for the total synthesis of the C 20-nor analogue of salvinorin A, was prepared in seven steps from 3-furaldehyde. Key steps involved a highly regioand diastereoselective Lewis acid assisted Diels-Alder reaction

Substituted 1,3-cyclohexadiene synthesis by NHC-Nickel(0) catalyzed [2+2+2] cycloaddition of 1,n-Enyne

This paper describes a catalytic and selective synthesis of substituted 1,3-cyclohexadiene fused with xH-pyran and furan. By using terminal enynes as substrates, NHC-Ni(0) as catalyst, and an ether as spacer between the two unsaturated hydrocarbon termini

A mild CuI-catalyzed Glaser-type homo-coupling reaction using α,α-dibromo-β-dicarbonyl compounds as oxidants

Exploration of α,α-dibromo-β-dicarbonyl compounds as novel organic oxidants for the mild Cu(I)-catalyzed Glaser-type homo-coupling reaction has been achieved, which provides an alternatively efficient pathway for the construction of 1,3-conjugated structures. In addition, the mechanism of this reaction was investigated.

Pt-catalyzed tandem 1,2-acyloxy migration/intramolecular [3 + 2] cycloaddition of enynyl esters

(Formula Presented) A platinum-catalyzed tandem reaction involving enynyl ester isomerization and subsequent intramolecular [3 + 2] cyclization has been developed. This strategy provides an efficient approach to five-, six-, or seven-membered cyclic polyfunctional compounds. Copyright

Bronsted acid-catalyzed three-component hosomi-sakurai reactions

Aldehydes react with silyl ethers or the corresponding alcohols and allylsilanes in the presence of catalytic amounts of 2,4-dinitrobenzenesulfonic acid (DNBA) to provide a wide range of homoallylic ethers in moderate to high yields.