5582-62-7

Basic information

• Product Name: PROPARGYLOXYTRIMETHYLSILANE
• Synonyms: Propargyl(trimethylsilyl) ether;Propargyloxytrimethylsilane,97%;3-Trimethylsiloxy-1-propyne,(Propargyloxy)trimethylsilane, O-(Trimethylsilyl)propargyl alcohol, Trimethyl(2-propynyloxy)silane, Trimethyl(propargyloxy)silane;O-TRIMETHYLSILYLPROPARGYL ALCOHOL 98%;triMethyl(prop-2-yn-1-yloxy)silane;3-TriMethylsiloxy-1-propyne 98%;Trimethyl(prop-2-yn-1-yloxy);2-Propynyl trimethylsilyl ether
• CAS NO: 5582-62-7
• Molecular Formula: C₆H₁₂OSi
• Molecular Weight: 128.24
• EINECS: 226-981-7
• Product Categories: Alkynes;Building Blocks;Chemical Synthesis;Organic Building Blocks;Terminal
• Mol File: 5582-62-7.mol
• Article Data: 28

Chemical Properties

• Melting Point: <0°C
• Boiling Point: 52 °C85 mm Hg(lit.)
• Flash Point: 48 °F
• Appearance: Clear yellow-brown/Liquid
• Density: 0.835 g/mL at 25 °C(lit.)
• Vapor Pressure: 23.6mmHg at 25°C
• Refractive Index: n20/D 1.408(lit.)
• Storage Temp.: Flammables area
• Sensitive: Moisture Sensitive
• BRN: 2036793
• CAS DataBase Reference: PROPARGYLOXYTRIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: PROPARGYLOXYTRIMETHYLSILANE(5582-62-7)
• EPA Substance Registry System: PROPARGYLOXYTRIMETHYLSILANE(5582-62-7)

Safety Data

• Hazard Codes: F
• Statements: 11
• Safety Statements: 16-23-24/25
• RIDADR: UN 1993 3/PG 2
• WGK Germany: 3
• F: 21
• TSCA: Yes
• HazardClass: 3
• PackingGroup: II
• Hazardous Substances Data: 5582-62-7(Hazardous Substances Data)

Usage

Uses

3-Trimethylsiloxy-1-propyne (Trimethyl(2-propynyloxy)silane) may be used in the synthesis of polytrialkylsiloxy-substituted macromolecules. It may be utilized in the preparation of functionalized 4-enynes and 1,4-dienes.

General Description

3-Trimethylsiloxy-1-propyne is an organosilicon compound. It is reported as silylated acetylenic monomer and its polymerizability has been studied in the presence of combined catalyst iron(III) propanoate-triethylaluminium. N2 laser light-induced aerosol particle formation from 3-trimethylsiloxy-1-propyne (trimethyl(2-propynyloxy)silane) and acrolein has been reported. The infrared laser-photosensitized (SF6) decomposition of trimethyl(2-propynyloxy)silane is reported to afford a multitude of unsaturated hydrocarbons and a solid polydimethylsiloxane phase.

InChI:InChI=1/C6H12OSi/c1-5-6-7-8(2,3)4/h1H,6H2,2-4H3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 1067-60-3 triethyl-prop-2-ynyloxy-stannane 
• 107-19-7 propargyl alcohol 
• 74-96-4 ethyl bromide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 104915-79-9 trimethyl-(1H,1H,9H-hexadecafluorononyloxy)silane 
• 56002-63-2 trimethyl-(1H,1H,5H-octafluoropentyloxy)silane 
• 56002-69-8 trimethyl-(1H,1H,3H-tetrafluoropropoxy)silane 
• 56002-71-2 trimethyl-(1H,1H,7H-dodecafluoroheptyloxy)silane 
• 43112-38-5 3-(trimethylsilyl)-2-oxazolidinone 

Downstream Products

• 107148-36-7 trimetyl<<3-(cyclohexen-1-yl)-2-propynyl>oxy>silane 
• 108461-99-0 2-Prop-2-ynyloxy-cyclohex-2-enone 
• 121284-47-7 (2,4,6-Tri-tert-butyl-phenyl)-(3-trimethylsilanyloxy-propenylidene)-phosphane 
• 3385-94-2 hexamethyldisilathiane 
• 5272-36-6 3-trimethylsilyl-2-propyn-1-ol 
• 96445-55-5 2,3-Dimethoxy-5-(trimethylsilyl)-6-<(oxy)methyl>-2,5-cyclohexadiene-1,4-dione 
• 22028-15-5 2,3-Dimethoxy-5-(hydroxymethyl)-2,5-cyclohexadiene-1,4-dione 
• 118041-81-9 2,3-Dimethoxy-5-<(oxy)methyl>-2,5-cyclohexadiene-1,4-dione 
• 21752-80-7 1,3-bis(trimethylsilyl)propyne 
• 2652-46-2 3-(triethylsilyl)prop-2-yn-1-ol 
• 215360-91-1 3-Methyl-5-trimethylsilanyloxymethyl-isoxazole 
• 102-07-8 bis(diphenyl)urea 
• 107-46-0 Hexamethyldisiloxane 
• 74-86-2 acetylene 

Relevant articles and documents

Chlorozincate(II) acidic ionic liquid: Efficient and biodegradable silylation catalyst

A practical and highly efficient silylation of alcohol and phenol derivatives with hexamethyldisilazane (HMDS) using acidic ionic liquids under mild reaction conditions is described. A series of Br?nsted as well as Br?nsted–Lewis acidic ionic liquids were prepared and their performance investigated for the silylation of a wide variety of alcohols and phenols with HMDS. Imidazole- as well as N-methyl-2-pyrrolidone-based acidic ionic liquids have a higher catalytic activity for the protection of sensitive, hindered alcohols and phenols, thus providing an environmentally begin and versatile alternative to current acid catalysts. In addition, the acidic ionic liquids are reusable, being recovered easily and reused several times without significant deterioration in catalytic activity.

Preparation of nano silica supported sodium hydrogen sulfate: As an efficient catalyst for the trimethyl, triethyl and t-butyldimethyl silylations of aliphatic and aromatic alcohols in solution and under solvent-free conditions

Nano silica supported sodium hydrogen sulfate has been prepared by mixing NaHSO4 with activated Nano silicagel. We wish to report a new method for the synthesis of trimethyl (TMS), triethyl (TES) and t-butyldimethyl silyl (TBS) ethers from benzylic, allylic, propargylic alcohols, phenols, naphtholes and some of phenolic drugs in the solution and under solvent-free conditions.

An expeditious, efficient green methodology for the Boc protection of amines and silyl protection of alcohols over tungstophosphoric acid-doped mesoporous silica

An efficient, chemoselective and eco-friendly protocol for the protection of amines as N-tert-butylcarbamate using (Boc)2O and protection of alcohols as silyl ether using HMDS over tungstophosphoric acid/SBA15 has been developed. Solventless condition, easy work-up, short reaction time, excellent yields and reusability of the catalyst are the striking features of this methodology which can be considered to be one of the better methods for the protection of amines and alcohols.