21353-16-2

Basic information

• Product Name: 7-Hydroxy-4-Methyl-2H-naphtho(1,2-B)pyran-2-one
• Synonyms: 7-Hydroxy-4-Methyl-2H-naphtho(1,2-B)pyran-2-one
• CAS NO: 21353-16-2
• Molecular Formula: C₁₄H₁₀O₃
• Molecular Weight: 226.2274
• Mol File: 21353-16-2.mol
• Article Data: 16

Chemical Properties

• Melting Point: 302-303 °C
• Boiling Point: 472.1°C at 760 mmHg
• Flash Point: 212.7°C
• Appearance: /
• Density: 1.349g/cm³
• Vapor Pressure: 1.54E-09mmHg at 25°C
• Refractive Index: 1.691
• PKA: 9.10±0.20(Predicted)
• CAS DataBase Reference: 7-Hydroxy-4-Methyl-2H-naphtho(1,2-B)pyran-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Hydroxy-4-Methyl-2H-naphtho(1,2-B)pyran-2-one(21353-16-2)
• EPA Substance Registry System: 7-Hydroxy-4-Methyl-2H-naphtho(1,2-B)pyran-2-one(21353-16-2)

Safety Data

• Hazardous Substances Data: 21353-16-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H10O3/c1-8-7-13(16)17-14-9(8)5-6-10-11(14)3-2-4-12(10)15/h2-7,15H,1H3

Upstream product

• 83-56-7 1,5-dihydroxynaphthalene 
• 105-45-3 acetoacetic acid methyl ester 
• 3588-80-5 5-methoxynaphthalen-1-ol 
• 141-97-9 ethyl acetoacetate 
• 7647-01-0 hydrogenchloride 
• 114397-85-2 1,5-bis-acetoacetyloxy-naphthalene 
• 628-13-7 pyridine hydrochloride 
• 674-82-8 4-methyleneoxetan-2-one 

Downstream Products

• 21353-27-5 7-methyl-2-phenyl-2,3-dihydro-1H-pyrano[2',3':5,6]naphtho[2,1-e][1,3]oxazin-9-one 
• 21353-25-3 2-benzyl-7-methyl-2,3-dihydro-1H-pyrano[2',3':5,6]naphtho[2,1-e][1,3]oxazin-9-one 
• 1374677-29-8 N-(3,4-dimethylbenzyl)-2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)acetamide 
• 1374677-28-7 N-(4-methoxybenzyl)-2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)acetamide 
• 1374677-27-6 N-benzyl-2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)acetamide 
• 1374677-26-5 2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)-N-(4-sulfamoylphenyl)acetamide 
• 1374677-25-4 2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)-N-(3,4,5-trimethoxyphenyl)acetamide 
• 1374677-24-3 3-(2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)acetamido)benzoic acid 
• 1374677-23-2 N-cyclohexyl-2-(4-methyl-2-oxo-2H-benzo[h]chromen-7-yloxy)acetamide 
• 1323444-51-4 (E)-8-acetyl-1-methyl-5-(3-oxo-3-p-tolylprop-1-enyl)chromeno[8,7-h]chromene-3,9-dione 
• 1323444-60-5 (E)-methyl 7-methyl-3,9-dioxo-11-(3-oxo-3-phenylprop-1-enyl)-3,9-dihydrochromeno[8,7-h]chromene-2-carboxylate 
• 1323444-59-2 (E)-ethyl 7-methyl-3,9-dioxo-11-(3-oxo-3-phenylprop-1-enyl)-3,9-dihydrochromeno[8,7-h]chromene-2-carboxylate 
• 1323444-53-6 (E)-methyl 7-methyl-3,9-dioxo-11-(3-oxo-3-p-tolylprop-1-enyl)-3,9-dihydrochromeno[8,7-h]chromene-2-carboxylate 
• 1323444-52-5 (E)-ethyl 7-methyl-3,9-dioxo-11-(3-oxo-3-p-tolylprop-1-enyl)-3,9-dihydrochromeno[8,7-h]chromene-2-carboxylate 

Relevant articles and documents

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The synthesis of a series of benzocoumarin keto-enamine schiff bases is reported. The novel compounds were evaluated for their antihyperlipidemic activity in the hyperlipidemic hamster model. The compound 11 at a dose of 10 mg/kg body weight significantly

Synthesis of 2H-4,8-dimethylthieno[2′,3′: 5,6]naphtho[1,2-b]pyran-2-one with potential photobiological activity to DNA

2H-4,8-Dimethylthieno[2′,3′:5,6]naphtho[1,2-b]pyran-2-one (7), a potential photobiological agent, was synthesized in six steps starting from commercially available 1,5-naphthalenediol. A Newman-Kwart rearrangement of naphthopyrone 2 and an unusual S-Claisen rearrangement of naphthopyrone 5 are the key steps. The structures of 7 and its precursors were fully characterized.

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