213606-47-4

Basic information

• Product Name: Diethyl-[2-(3-nitrophenoxy)ethyl]aMine
• Synonyms: Diethyl-[2-(3-nitrophenoxy)ethyl]aMine
• CAS NO: 213606-47-4
• Molecular Formula: C₁₂H₁₈N₂O₃
• Molecular Weight: 238.28292
• Product Categories: Aromatics, Miscellaneous Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 213606-47-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 351.6±22.0 °C(Predicted)
• Appearance: /
• Density: 1.107±0.06 g/cm3(Predicted)
• PKA: 9.47±0.25(Predicted)
• CAS DataBase Reference: Diethyl-[2-(3-nitrophenoxy)ethyl]aMine(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl-[2-(3-nitrophenoxy)ethyl]aMine(213606-47-4)
• EPA Substance Registry System: Diethyl-[2-(3-nitrophenoxy)ethyl]aMine(213606-47-4)

Safety Data

• Hazardous Substances Data: 213606-47-4(Hazardous Substances Data)

Usage

Uses

Diethyl-[2-(3-nitrophenoxy)ethyl]amine is an intermediate in the synthesis of RAGE inhibitors. Also a shows activity in plant growth retardation.

Upstream product

• 554-84-7 meta-nitrophenol 
• 869-24-9 2-chloro-N,N-diethylethylamine hydrochloride 
• 13831-59-9 2-(3-nitrophenoxy)bromoethane 
• 109-89-7 diethylamine 

Downstream Products

• 34334-19-5 3-(2-diethylamino-ethoxy)-phenylamine 

Relevant articles and documents

Novel heteroarylcarboxamide derivative or pharmacutically acceptable salt thereof, process for the preparation thereof and pharmaceutical composition for prevention or treatment of RAGE receptor related diseases containing the same as an active ingredient

The present invention refers to novel heterocyclic biting Carbox probably the id derivative acceptable salt, and manufacturing method thereof including RAGE associated active acetylcholinesterase receptor or pharmaceutical composition for preventing or treating disease is directed to. Heterocycle by the present invention a derivative biting Carbox probably the id RAGE receptor antagonism in by, nerve cells with the beta loss oh with wheat id RAGE conjunction with receptor, inhibiting moving into brain, the resulting beta Amyloid plaque formed 21 is known to effectively inhibit generation.. Furthermore, memory a chemicals that are important in the acetylcholine for decomposing an aromatic thus inhibiting acetylcholine s reel sacrifice , RAGE disease associated active acetylcholinesterase receptor or Alzheimer's disease, cerebrovascular dementia, dementia due to damage bean curd, multi blockade dementia, Alzheimer's disease or the like dementia alcoholic or mixed dementia multi blockade and including dementia, pick (pick) bottle, a smartcrew [...] -Jakob (Creutzfeldt-jakob) bottle, that thyroid gland symptoms , bean curd a blade Parkinson (Parkinson) bottle, Huntington's disease (Huntington) which is useful in preventing or treating, can be used.

Synthesis of Quaternary Salts of Ammonia from Phenols and their Plant Growth Retardant Activity

Different phenols, viz. β-naphthol, p-chlorophenol, p-cresol and m-nitrophenol have been converted into (3-diethylamino-2-hydroxypropyloxy) derivatives (4a-d) through the formation of glycidyl ethers (2a-d and 3a-d). m-Nitrophenol and p-chlorophenol have been converted to 2-aryloxy-N,N-diethylaminoethanes (8e,f) through the formation of bromoethers (7e,f). 1,3-Bis(2-diethylaminoethoxy)benzene (12) has been prepared from resorcinol. The tertiary amines (4a-d, 8e,f and 12) are then quaternized with citronellyl bromide and tested as plant growth retardants.