214550-36-4

Basic information

• Product Name: 1H-2-Benzopyran, 3,4-dihydro-3-(4-methoxyphenyl)-
• CAS NO: 214550-36-4
• Molecular Formula: C16H16O2
• Molecular Weight: 240.302
• Mol File: 214550-36-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran, 3,4-dihydro-3-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran, 3,4-dihydro-3-(4-methoxyphenyl)-(214550-36-4)
• EPA Substance Registry System: 1H-2-Benzopyran, 3,4-dihydro-3-(4-methoxyphenyl)-(214550-36-4)

Safety Data

• Hazardous Substances Data: 214550-36-4(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 100-44-7 benzyl chloride 
• 50-00-0 formaldehyd 
• 5422-47-9 1-(4-methoxyphenyl)-2-phenylethan-1-ol 

Downstream Products

• 29910-92-7 3-(4-methoxyphenyl)-1H-isochromen-1-one 
• 37568-81-3 3,4-dihydro-3-(4-methoxyphenyl)-1H-2-benzopyran-1-one 
• 33533-90-3 2-[2-oxo-2-(4'-methoxyphenyl)ethyl]benzoic acid 
• 257882-74-9 2-[2-oxo-2-(4'-methoxyphenyl)ethyl]benzaldehyde 

Relevant articles and documents

Intermolecular oxyarylation of olefins with aryl halides and TEMPOH catalyzed by the phenolate anion under visible light

The phenolate anion was discovered as a new photocatalyst with strong reduction potentials. Under visible light irradiation, the phenolate anion enabled the reduction of (hetero)aryl halides (including electron-rich aryl chlorides) to (hetero)aryl radicals through single electron transfer. Based on this new photocatalyst, a novel and efficient photocatalytic protocol for the intermolecular oxyarylation of olefins with aryl halides and TEMPOH was developed. The developed three-component coupling reaction proceeded under redox-neutral reaction conditions with stable and readily available synthons and exhibited broad substrate scope. The utility of this process was further highlighted by the diversified chemical manipulation of the resulting oxyarylation products and the late-stage modification of active pharmaceutical ingredients.

Improved procedure for 3,4-dihydro-1H-2-benzopyran ring closure. A general access to 3-substituted isochromanes

A general method for the ring closure of 1-substituted 2-(- hydroxymethyl)-phenylethanols to 3-substituted isochromanes using p-TsOH supported on silica gel is reported.