21504-07-4Relevant articles and documents
Difunctionalization of Alkynones by Base-Mediated Reaction with α,α-Dithioketones
Yang, Yajie,Cheng, Lu,Wang, Mengdan,Yin, Liqiang,Feng, Ye,Wang, Chengyu,Li, Yanzhong
, p. 5339 - 5343 (2021)
A novel 1,2-difunctionalization of alkynones via an umpolung strategy for the synthesis of tetrasubstituted olefins has been developed. This procedure is realized by a formal C-C σ-bond cleavage reaction of cyclic α,α-dithioketones and subsequent deprotection. Notable features of this approach include excellent yields, mild reaction conditions, a broad substrate scope, and operational simplicity.
1,3-Dithianes as Acyl Anion Equivalents in Pd-Catalyzed Asymmetric Allylic Substitution
Yao, Kun,Liu, Delong,Yuan, Qianjia,Imamoto, Tsuneo,Liu, Yangang,Zhang, Wanbin
supporting information, p. 6296 - 6299 (2016/12/23)
A Pd-catalyzed asymmetric allylic substitution with 1,3-dithianes as acyl anion equivalents has been developed in high yields and excellent enantioselectivities. The reaction was performed on a gram scale, and the corresponding alkylated products were con
Synthetic equivalents based on Weinreb amide functionality for convenient access to monoprotected α-diketones
Balasubramaniam, Sivaraman,Aidhen, Indrapal Singh
, p. 959 - 963 (2008/02/02)
A convenient new strategy for the synthesis of monoprotected α-diketones has been achieved. The strategy is based on the use of hitherto unreported N-methoxy-N-methyl-1,3-dithiolane-2-carboxamide and N-methoxy-N-methyl-1,3-dithiane-2-carboxamide as synthe
