215116-94-2

Upstream product

• 215117-45-6 4-Oxo-pentanoic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-(4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-2-oxo-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 3992-42-5 2'-deoxycytidine monohydrochloride 
• 951-77-9 2'-Deoxycytidine 
• 80594-29-2 1-{(2R,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-4-{[bis-(4-methoxy-phenyl)-phenyl-methyl]-amino}-1H-pyrimidin-2-one 
• 123-76-2 levulinic acid 

Downstream Products

• 215117-08-1 5'-O-(4,4'-dimethoxytrityl)-P-(2-cyanoethyl)-T(6-4)C 3'-levulinate 
• 215117-15-0 5'-O-(4,4'-dimethoxytrityl)-P-(2-cyanoethyl)-T(6-4)C 

Relevant academic research and scientific papers

Chemical synthesis of oligonucleotides containing the (6-4) photoproduct at the thymine-cytosine site and its repair by (6-4) photolyase

A phosphoramidite building block of the T(6-4)C photoproduct was synthesized. One of the differences from T(6-4)T was formation of cytosine hydrates by UV irradiation, and the other was acylation of the amino function with the capping reagent. The capping

Studies on the chemical synthesis of oligonucleotides containing the (6- 4) photoproduct of thymine-cytosine and its repair by (6-4) photolyase

To prepare oligonucleotides containing the pyrimidine(6-4)pyrimidone photoproduct between thymine and cytosine, which is formed more efficiently than any counterpart at other dipyrimidine sites, a dimer building block of this photoproduct was synthesized.