215675-07-3

Upstream product

• 117937-01-6 4-(4-bromophenyl)-4-hydroxybut-2-ynoic acid ethyl ester 
• 1122-91-4 4-bromo-benzaldehyde 
• 623-47-2 propynoic acid ethyl ester 
• 1777-57-7 p-bromobenzoylmethylenetriphenylphosphorane 

Downstream Products

• 923286-35-5 3-(4-bromo-benzoyl)-4-ethyl-5,6-dimethyl-8,8-diphenyl-4,8-dihydro-1-oxa-7-thia-4-aza-azulene-2-carboxylic acid ethyl ester 
• 1005385-92-1 C₂₆H₃₀BrNO₄S 
• 1005385-90-9 C₂₉H₃₀BrNO₄S 
• 1005385-98-7 3-ethyl-4,5-dimethylthiazol-2(3H)-one 
• 1005385-91-0 C₂₈H₂₈BrNO₄S 
• 1005385-93-2 C₂₃H₂₆BrNO₄S 
• 1311146-57-2 5-[(4-bromophenyl)difluoromethyl]-3-methylisoxazole-4-carboxylic acid ethyl ester 
• 1311146-58-3 4-[(4-bromophenyl)difluoromethyl]-3-methylisoxazole-5-carboxylic acid ethyl ester 
• 1311146-39-0 4-(4-bromophenyl)-4,4-difluorobut-2-ynoic acid ethyl ester 
• 1311146-40-3 2-[(4-bromophenyl)difluoromethyl]-4,5-dimethylcyclohexa-1,4-dienecarboxylic acid ethyl ester 

Relevant academic research and scientific papers

A new flexible strategy for the synthesis of gem-difluoro-bisarylic derivatives and heterocyclic analogues

A new strategy has been designed for the preparation of gem-difluoro-bisarylic derivatives. It starts from easily accessible and reactive gem-difluoro-propargylic intermediates and elaborates the aromatic rings by a Diels-Alder-aromatization sequence. Het

Oxalylmethylenephosphoranes: III. Synthesis and Flash Vacuum Pyrolysis of Ethyl 4-Aryl-3-triphenylphosphoranylidene-2,4-dioxobutanoates

Ethyl 4-aryl-3-triphenylphosphoranylidene-2,4-dioxobutanoates were obtained by C-acylation of (aroylmethylene)(triphenyl)phosphorane with ethyl oxalyl chloride. Under conditions of vacuum flash pyrolysis at 500°C the former eliminate triphenylphosphine oxide to give ethyl 4-aryl-4-oxo-2-butynoates.