2157-16-6

Basic information

• Product Name: 1 4-BUTANEDIOL BIS(CHLOROFORMATE) 97
• Synonyms: 1 4-BUTANEDIOL BIS(CHLOROFORMATE) 97;tetramethylene bis(chloroformate);1,4-Butanediol di(chloroformate);Bis(chloroformic acid)1,4-butanediyl;Bis(chloroformic acid)tetramethylene ester;Butane-1,4-diol bis(chloroformate);BUTANE-1,4-DIYL DICARBONOCHLORIDATE
• CAS NO: 2157-16-6
• Molecular Formula: C₆H₈Cl₂O₄
• Molecular Weight: 215.03132
• EINECS: 218-466-0
• Product Categories: Acid Halides;Carbonyl Compounds;Organic Building Blocks
• Mol File: 2157-16-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 211-212 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.330 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0328mmHg at 25°C
• Refractive Index: n20/D 1.4530(lit.)
• CAS DataBase Reference: 1 4-BUTANEDIOL BIS(CHLOROFORMATE) 97(CAS DataBase Reference)
• NIST Chemistry Reference: 1 4-BUTANEDIOL BIS(CHLOROFORMATE) 97(2157-16-6)
• EPA Substance Registry System: 1 4-BUTANEDIOL BIS(CHLOROFORMATE) 97(2157-16-6)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 1760 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 2157-16-6(Hazardous Substances Data)

Usage

General Description

1,4-Butanediol bis(chloroformate) 97 is a chemical compound that is commonly used as a reagent in organic synthesis. It is a colorless liquid with a mild, pleasant odor, and is highly soluble in water. 1 4-BUTANEDIOL BIS(CHLOROFORMATE) 97 is used as a cross-linking agent in the production of polymers and resins, and also as a reagent in the preparation of various pharmaceuticals and agrochemicals. It is considered to be a hazardous chemical and should be handled with care, as it can cause skin and eye irritation, and may be harmful if ingested or inhaled.

InChI:InChI=1/C6H8Cl2O4/c7-5(9)11-3-1-2-4-12-6(8)10/h1-4H2

Upstream product

• 75-44-5 phosgene 
• 110-63-4 Butane-1,4-diol 

Downstream Products

• 110-56-5 1,4-dichlorobutane 
• 7119-55-3 butane-1,4-diyl dicarbamate 
• 56456-35-0 C₂₂H₂₀I₆N₄O₈ 
• 60226-44-0 C₂₂H₂₈N₆O₁₀S₂ 
• 144370-08-1 1,4-bis-(4-carboxy-phenylcarbamoyloxy)-butane 

Relevant articles and documents

Method for the preparation of aliphatic chloroformates

A method for preparing an aliphatic chloroformate comprising, introducing a mixture of at least one aliphatic hydroxyl compound, phosgene, at least one solvent, and optionally at least one organic base into a flow reactor to obtain a unidirectional flowing reaction mixture. The at least one aliphatic hydroxyl compound comprises at least one aliphatic hydroxyl group. The unidirectional flowing reaction mixture is maintained at a temperature between about 0° C. and about 60° C. to produce a single product stream comprising an aliphatic chloroformate.

Oxyformamidates

Compounds of the formula STR1 WHEREIN A is a linking group, X is an O--CO-- or --SO2 -- group and n is at least 2, are prepared from the corresponding N',N'-disubstituted hydrazides by quaternization and treatment with alkali or reaction with an alkylene epoxide or from the corresponding compound wherein n = 1 and A is a polymerizable group by polymerization. The compounds are unstable to heat and may be used as cross-linking agents for polymers or as chain-extending agents, bonding agents or adhesives.