21573-38-6

Basic information

• Product Name: 1-methoxy-2,4,5-trimethylbenzene
• Synonyms: 1-methoxy-2,4,5-trimethylbenzene
• CAS NO: 21573-38-6
• Molecular Weight: 150.221
• Mol File: 21573-38-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-methoxy-2,4,5-trimethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-methoxy-2,4,5-trimethylbenzene(21573-38-6)
• EPA Substance Registry System: 1-methoxy-2,4,5-trimethylbenzene(21573-38-6)

Safety Data

• Hazardous Substances Data: 21573-38-6(Hazardous Substances Data)

Upstream product

• 95-63-6 1,2,4-Trimethylbenzene 
• 64-19-7 acetic acid 
• 496-78-6 2,4,5-trimethylphenol 
• 95-65-8 3,4-Dimethylphenol 
• 74-88-4 methyl iodide 
• 1706-11-2 2,5-Dimethyl-anisol 
• 67-56-1 methanol 
• 79-21-0 peracetic acid 
• 6745-75-1 2,5-dimethyl-p-anisaldehyde 

Downstream Products

• 496-78-6 2,4,5-trimethylphenol 
• 780771-26-8 2,3,4,6-tetramethyl-anisole 
• 3238-38-8 isodurenol 
• 722495-58-1 2-methoxy-3,5,6-trimethyl-benzaldehyde 

Relevant articles and documents

Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum

The volatiles emitted by the ascomycetes Hypoxylon griseobrunneum and Hypoxylon macrocarpum (Hypoxylaceae, Xylariales) were collected by use of a closed-loop stripping apparatus (CLSA) and analysed by GC-MS. The main compound class of both species were polysubstituted benzene derivatives. Their structures could only be unambiguously determined by comparison to all isomers with different substitution patterns. The substitution pattern of the main compound from H. griseobrunneum, the new natural product 2,4,5-trimethylanisole, was explainable by a polyketide biosynthesis mechanism that was supported by a feeding experiment with (methyl-2H3)methionine.

REACTION OF 1,2,4-TRIMETHYLBENZENE WITH PERACETIC ACID

The oxidation of 1,2,4-trimethylbenzene with peracetic acid leads to the formation of trimethylphenols and hydroquinones, which undergo transformations to the corresponding benzoquinones and products from oxidative cleavage of the ring.The controlling stage of the process is the electrophilic hydroxylation of 1,2,4-trimethylbenzene.