496-78-6Relevant articles and documents
Aromatics to diquinanes: An expeditious synthesis of tetramethylbicyclo[3. 3.0]octane framework of ptychanolide
Singh, Vishwakarma,Chandra, Girish,Mobin, Shaikh M.
, p. 3111 - 3114 (2008)
An expeditious route to methyl-7-oxo-1,4,5,8-tetramethylbicyclo[3.3.0] octane-3-carboxylate from a simple aromatic precursor is described. Oxidative dearomatization of 2-hydroxymethyl-3,4,6-trimethylphenol into spiroepoxycyclohexa-2,4-dienone, its cycloaddition and triplet-sensitized 1,2-acyl shift, and stereochemical inversion are the key features of our methodology. Georg Thieme Verlag Stuttgart.
Volatiles from the hypoxylaceous fungi Hypoxylon griseobrunneum and Hypoxylon macrocarpum
Rinkel, Jan,Babczyk, Alexander,Wang, Tao,Stadler, Marc,Dickschat, Jeroen S.
, p. 2974 - 2990 (2019/01/05)
The volatiles emitted by the ascomycetes Hypoxylon griseobrunneum and Hypoxylon macrocarpum (Hypoxylaceae, Xylariales) were collected by use of a closed-loop stripping apparatus (CLSA) and analysed by GC-MS. The main compound class of both species were polysubstituted benzene derivatives. Their structures could only be unambiguously determined by comparison to all isomers with different substitution patterns. The substitution pattern of the main compound from H. griseobrunneum, the new natural product 2,4,5-trimethylanisole, was explainable by a polyketide biosynthesis mechanism that was supported by a feeding experiment with (methyl-2H3)methionine.
Thermal hazard evaluation of cumene hydroperoxide-metal ion mixture using DSC, TAM III, and GC/MS
You, Mei-Li
, (2016/06/15)
Cumene hydroperoxide (CHP) is widely used in chemical processes, mainly as an initiator for the polymerization of acrylonitrile-butadiene-styrene. It is a typical organic peroxide and an explosive substance. It is susceptible to thermal decomposition and is readily affected by contamination; moreover, it has high thermal sensitivity. The reactor tank, transit storage vessel, and pipeline used for manufacturing and transporting this substance are made of metal. Metal containers used in chemical processes can be damaged through aging, wear, erosion, and corrosion; furthermore, the containers might release metal ions. In a metal pipeline, CHP may cause incompatibility reactions because of catalyzed exothermic reactions. This paper discusses and elucidates the potential thermal hazard of a mixture of CHP and an incompatible material's metal ions. Differential scanning calorimetry (DSC) and thermal activity monitor III (TAM III) were employed to preliminarily explore and narrate the thermal hazard at the constant temperature environment. The substance was diluted and analyzed by using a gas chromatography spectrometer (GC) and gas chromatography/mass spectrometer (GC/MS) to determine the effect of thermal cracking and metal ions of CHP. The thermokinetic parameter values obtained from the experiments are discussed; the results can be used for designing an inherently safer process. As a result, the paper finds that the most hazards are in the reaction of CHP with Fe2+. When the metal release is exothermic in advance, the system temperature increases, even leading to uncontrollable levels, and the process may slip out of control.