78775-11-8Relevant articles and documents
A substituted benzamide isoxazoline derivative or a salt thereof as a pesticidally acceptable salt. Composition and use thereof
-
Paragraph 0109-0112, (2021/10/30)
The invention belongs to the field of pesticides, and particularly relates to a substituted benzamide isoxazoline derivative or a salt, composition and application thereof as a pesticide acceptable salt, and the compound has the structure of the formula (
Fluorine thramine intermediate and method for preparing flumbine by using same
-
Paragraph 0111-0114; 0122-0125, (2021/12/07)
The invention discloses a fluororesonide intermediate and a method for preparing the same, and a fluororesonide intermediate -5. Routes include the use of m-xylene as starting materials, halogenation. Oxidation reaction The intermediate -5 is further obtained by hydroximation, cyanolation, hydrolysis reaction or cyanation, oximation, and hydrolysis reaction. As some examples of the present invention, synthetic routes were increased 2 steps from 5 steps in the prior art, but surprisingly high overall yields were obtained and the purity of intermediate -5 was significantly increased. , The starting material of the intermediate -5 is prepared from high 4 - bromo -2 - methylbenzoic acid to low-priced m-xylene, so that the cost of the intermediate -5 is greatly reduced. , The reaction condition is mild, the synthesis difficulty is low, and the environment is more environmentally friendly.
As opioid receptor antagonists or inverse agonists of the novel compounds
-
Paragraph 0602-0604, (2016/10/08)
Novel compounds which are antagonists or inverse agonists at one or more of the opioid receptors, pharmaceutical compositions containing them, to processes for their preparation.