216481-88-8

Basic information

• Product Name: (+)-cis-2-amino-6-chloro-9-<(4'R)-(hydroxymethyl)cyclopent-2'-en-(1'S)-yl>purine
• CAS NO: 216481-88-8
• Molecular Weight: 265.702
• Mol File: 216481-88-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (+)-cis-2-amino-6-chloro-9-<(4'R)-(hydroxymethyl)cyclopent-2'-en-(1'S)-yl>purine(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-cis-2-amino-6-chloro-9-<(4'R)-(hydroxymethyl)cyclopent-2'-en-(1'S)-yl>purine(216481-88-8)
• EPA Substance Registry System: (+)-cis-2-amino-6-chloro-9-<(4'R)-(hydroxymethyl)cyclopent-2'-en-(1'S)-yl>purine(216481-88-8)

Safety Data

• Hazardous Substances Data: 216481-88-8(Hazardous Substances Data)

Upstream product

• 10310-21-1 2-amino-6-chloropurine 
• 137821-19-3 (1R,4S)-(+)-4-acetoxy-1-(triphenylmethoxymethyl)cyclopent-2-ene 
• 110289-12-8 (+/-)-(1β,4β)-1-(triphenylmethoxymethyl)cyclopent-2-en-4-ol 
• 151765-20-7 (1S,5S)-5-hydroxymethyl-2-cyclopenten-1-ol 
• 267411-98-3 (4S,5R)-3-((1S,2S)-2-Benzyloxymethyl-2-ethoxy-4-oxo-cyclopentyl)-4,5-diphenyl-oxazolidin-2-one 
• 267411-96-1 (4S,5R)-3-((1S,2R)-2-Benzyloxymethyl-4-oxo-cyclopentyl)-4,5-diphenyl-oxazolidin-2-one 
• 267411-95-0 (4S,5R)-3-((S)-2-Benzyloxymethyl-4-oxo-cyclopent-2-enyl)-4,5-diphenyl-oxazolidin-2-one 
• 267411-97-2 Carbonic acid (1S,4R)-4-benzyloxymethyl-cyclopent-2-enyl ester ethyl ester 
• 261511-22-2 (1S)-cis-4-Benzyloxymethylcyclopent-2-en-1-ol 
• 159163-55-0 9-((1S,4R)-4-Benzyloxymethyl-cyclopent-2-enyl)-6-chloro-9H-purin-2-ylamine 
• 10310-21-1 2-Amino-6-chloropurin 
• 159248-77-8 Carbonic acid (1R,4S)-4-(2-amino-6-chloro-purin-9-yl)-cyclopent-2-enylmethyl ester methyl ester 
• 137782-35-5 (+)-cis-2-amino-6-chloro-9'-<(4'R)-(triphenylmethoxymethyl)cyclopent-2'-en-(1'S)-yl>purine 

Downstream Products

• 124915-24-8 (+)-carbovir 
• 128131-83-9 (+)-1592U89 
• 124915-24-8 (+)-carbovir 

Relevant articles and documents

Practical enantiodivergent syntheses of both enantiomers of carbovir, 1592U89 and six-membered ring analogues

The hydroxylactones 4a-b (both available in optically pure form from biocatalytic processes) have been used in the preparation of carbovir, 1592U89, and their six-membered ring analogues.

[2+3]-cycloadditions of enantiomerically pure oxazoline-N-oxides1 : A short stereoselective synthesis of (+)-carbovir

A short stereo selective synthesis of the potent antiviral agent carbovir 1 has been achieved by using a new [2+3] asymmetric cycloaddition between oxazoline-N-oxide 3 and cyclopentadiene.