21653-10-1Relevant academic research and scientific papers
N-(Aroyl)-N-(arylmethyloxy)-α-alanines: Selective inhibitors of aldose reductase
Nencetti, Susanna,La Motta, Concettina,Rossello, Armando,Sartini, Stefania,Nuti, Elisa,Ciccone, Lidia,Orlandini, Elisabetta
, p. 3068 - 3076 (2017/05/25)
Aldose reductase (ALR2), a NADPH-dependent reductase, is the first and rate-limiting enzyme of the polyol pathway of glucose metabolism and is implicated in the pathogenesis of secondary diabetic complications. In the last decades, this enzyme has been ta
