21737-13-3

Basic information

• Product Name: 2-Propenal, 3-phenyl-, oxime, (1E)-
• CAS NO: 21737-13-3
• Molecular Formula: C9H9NO
• Molecular Weight: 147.177
• Mol File: 21737-13-3.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: 2-Propenal, 3-phenyl-, oxime, (1E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenal, 3-phenyl-, oxime, (1E)-(21737-13-3)
• EPA Substance Registry System: 2-Propenal, 3-phenyl-, oxime, (1E)-(21737-13-3)

Safety Data

• Hazardous Substances Data: 21737-13-3(Hazardous Substances Data)

Upstream product

• 1028432-12-3 C₂₂H₃₁NO₃SSi 
• 14371-10-9 (E)-3-phenylpropenal 
• 524-38-9 N-hydroxyphthalimide 
• 96-29-7 ethyl methyl ketone oxime 
• 104-55-2 3-phenyl-propenal 
• 4335-60-8 (E)-cinnamylamine 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 4360-51-4 cinnamylamine 
• 20707-70-4 cinnamaldehyde-(Z)-oxime 
• 69415-53-8 benzoyl cinnamaldehyde oxime 

Downstream Products

• 131934-06-0 3,3-Diphenyl-propionaldehyde oxime 
• 621-79-4 cinnamamide 
• 129610-15-7 (E)-3-styryl-5-methyl-1,2,4-oxadiazole 
• 129849-64-5 Methyl N-Acetyl-1,2,3,4-tetrahydro-(3S^*,4S^*)-4-phenyl-6-cyanonicotinate 
• 129849-64-5 trans-Methyl N-Acetyl-1,2,3,4-tetrahydro-4-phenyl-6-cyanonicotinate 
• 129849-58-7 N-Acetyl-1,2,3,4-tetrahydro-(2R^*,3S^*,4S^*)-2-methyl-3,4-diphenyl-6-cyanopyridine 
• 129849-58-7 N-Acetyl-1,2,3,4-tetrahydro-(2S^*,3S^*,4S^*)-2-methyl-3,4-diphenyl-6-cyanopyridine 
• 129849-58-7 N-Acetyl-1,2,3,4-tetrahydro-(2S^*,3R^*,4S^*)-2-methyl-3,4-diphenyl-6-cyanopyridine 
• 129849-58-7 N-Acetyl-1,2,3,4-tetrahydro-(2R^*,3R^*,4S^*)-2-methyl-3,4-diphenyl-6-cyanopyridine 
• 129849-55-4 N-Acetyl-1,2,3,4-tetrahydro-(2S^*,3S^*,4S^*)-2,3-(1',3'-cyclopentanediyl)-4-phenyl-6-cyanopyridine 
• 129849-62-3 N-Acetyl-1,2,3,4-tetrahydro-(2S^*,4S^*)-2-butyl-4-phenyl-6-cyanopyridine 
• 129849-54-3 N-Acetyl-1,2,3,4-tetrahydro-(2R^*,4S^*)-2-ethoxy-4-phenyl-6-cyanopyridine 
• 124643-76-1 1,2,3,8,9,9a-Hexahydro-(8S^*,9aS^*)-6-cyano-8-phenyl-4-quinolizinone 
• 124643-73-8 1,7,8,8a-Tetrahydro-(7S^*,8aS^*)-5-cyano-7-phenyl-3-(2H)-indolizinone 

Relevant articles and documents

Selective and facile synthesis of α,β-unsaturated nitriles and amides with N-hydroxyphthalimide as the nitrogen source

The direct conversion of α,β-unsaturated aldehydes to corresponding nitriles promoted by Pd(OAc)2 and phthalic acid which was hydrolyzed from N-hydroxyphthalimide (NHPI) has been disclosed. Additionally, it was found that when water was used as the solvent, α,β-unsaturated amides was obtained as the main products in good to excellent yields. It was first reported that NHPI was utilized as the nitrogen source to synthesize α,β-unsaturated nitriles and amides from aldehydes. Control experiment demonstrated that aldehydes undergo a process of oximation and dehydration to form nitriles and amides.

METHOD FOR PRODUCING ALDOXIME COMPOUND

PROBLEM TO BE SOLVED: To provide a method for producing an aldoxime compound using no expensive catalysts and reagents and also requiring no severe reaction conditions. SOLUTION: There is provided a method for producing an aldoxime compound containing a process where an aldehyde compound and an oxime compound are brought into trans oximation reaction in the presence of perchloric acid and/or the metallic salt of perchloric acid in an organic solvent and water. The metallic salt of perchloric acid is preferably ferric perchlorate, cobalt perchlorate, nickel perchlorate, zinc perchlorate, aluminum perchlorate or calcium perchlorate. Also, the organic solvent is preferably methylene chloride and/or ethylene dichloride. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

One-pot two-step sequential transformation: Highly efficient construction of o-2,3,5,6-tetrafluorobenzonitrile substituted oximes ethers

A practical variety of o-2,3,5,6-tetrafluorobenzonitrile substituted oximes ethers bearing broad functional groups were synthesized in moderate to good yields. The key highlight of this disclosure involving a one-pot two-step tandem procedure in aqueous media: the in situ formation of aryl aldehydes or ketones oximes followed by the SNAr reaction with pentafluorobenzonitrile via the high selective CF bond cleavage.