21743-58-8

Usage

Tetrazole derivative

PTAA is derived from a tetrazole, which is a five-membered heterocyclic ring system consisting of four nitrogen atoms and one carbon atom.

Contains a phenyl group

The compound has a phenyl group (a six-membered carbon ring with hydrogen atoms) attached to the tetrazole core.

Building block for synthesis

PTAA is primarily used as a building block for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals.

Potential applications as a corrosion inhibitor

PTAA has been studied for its ability to prevent or reduce corrosion in materials.

Intermediate in the production of dyes

The compound is also used as an intermediate in the synthesis of dyes.

Materials science applications

PTAA has been investigated for its potential use in the development of materials, particularly in the field of optoelectronics.

Component in organic light-emitting diodes (OLEDs)

PTAA may be used as a component in the development of OLEDs, which are devices that emit light when an electric current is applied.

Upstream product

• 614-20-0 3-oxo-3-phenylpropionic acid 
• 7647-01-0 hydrogenchloride 
• 42606-00-8 ethyl 5-phenyl-1H-tetrazolylacetate 
• 64-19-7 acetic acid 
• 131647-65-9 methyl 2-(5-phenyl-1H-tetrazole-1-yl)acetate 
• 1499-53-2 ethyl hippurate 

Downstream Products

• 109443-73-4 (5-phenyl-tetrazol-1-yl)-acetic acid-(2-diethylamino-ethyl ester); hydrochloride 
• 149942-24-5 (5-phenyltetrazol-1-yl)-acetic acid 2-hydroxyethyl ester 

Relevant academic research and scientific papers

Ramoplanin derivatives possessing antibacterial activity

Novel ramoplanin derivatives are disclosed. These ramoplanin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against gram positive bacteria, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.

TETRAZOLE DERIVATIVES AND ALDOSE REDUCTASE INHIBITION THEREWITH

The present invention relates to an aldose reductase inhibitor having the following formula: R1 is a hydrogen atom or --A--COOR5 (A is an alkylene group having 1 to 4 carbon atoms and R5 is a hydrogen atom or a lower alkyl group), and R2, R3 and R4 are the same as or different from each other and selected from the group consisting of a hydrogen atom, a hydroxy group, a halogen atom, a carboxyl group, an alkyl group, an amide group, an amino group, an alkoxy group, an aryl group, an aryloxy group, an alkylthio group, an alkylsulfinyl group, an alkylsulfonyl group, a nitro group, --NHCOCOOR6 (R6 is a hydrogen atom or a lower alkyl group), a mono or dialkylaminosulfonyl group, and a residual group having the following formula: (A and R5 are the same as in the above). The compounds defined in the above are excellent in aldose reductase inhibitory activity and low in toxicity. Therefore, those compounds are useful as a preventive agent and/or a remedy for diabetic complications such as neuropathy, retinopathy, nephropathy, cataracts and keratopathy